{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T10:25:38Z","timestamp":1777803938330,"version":"3.51.4"},"reference-count":44,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T00:00:00Z","timestamp":1633305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015736","name":"Folkh\u00e4lsanin Tutkimuss\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015736","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004212","name":"P\u00e4ivikki ja Sakari Sohlbergin S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004212","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010600","name":"Tays","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010600","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Obesity"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The incidences of both paediatric obesity and autoimmune diseases have been increasing, but their relationship with one another is unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether obesity or particular dietary patterns in school\u2010aged children are potential risk factors for autoimmune diseases during adolescence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This matched case\u2013control study included 525 children, followed up from a median age of 11.3 to 16.7\u2009years. Of them, 105 children received primary autoimmune diagnoses (diabetes, thyroiditis, arthritis, or inflammatory bowel diseases) after baseline and generated the case group. Four children with matching age, sex, and residential area generated the control group of 420 children. At baseline, age\u2010 and sex\u2010specific body mass index categories were acquired and waist\u2010to\u2010height ratio (WHTR) was calculated. Central obesity was present when WHTR \u22650.5. Dietary patterns were analysed using a food frequency questionnaire (FFQ).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>School\u2010aged children with central obesity were 2.11 (OR, 95% CI 1.11\u20133.98) times more likely to develop autoimmune diseases before age of 19\u2009years than those without central obesity. Being overweight was not related to the onset of these diseases (OR 1.60, 95% CI 0.89\u20132.87, nor were dietary patterns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Central obesity in school\u2010aged children was related to the development of autoimmune diseases, while being overweight and dietary patterns were not.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijpo.12857","type":"journal-article","created":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T22:35:44Z","timestamp":1633559744000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Central obesity in school\u2010aged children increases the likelihood of developing paediatric autoimmune diseases"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4892-5710","authenticated-orcid":false,"given":"Laura","family":"R\u00e4is\u00e4nen","sequence":"first","affiliation":[{"name":"Fin\u2010HIT Research 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