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Delay discounting is a cognitive process of comparison of valuation between immediate and delayed reward, which has been inconsistently linked to weight status. Moreover, central to the brain's reward system is the nucleus accumbens, a region structurally and functionally altered in obesity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives\/Methods<\/jats:title><jats:p>This study aimed to examine the relationships between two continuous metrics of weight status, performance on a monetary delay\u2010discounting task and nucleus accumbens functional connectivity in 10\u201312\u2010year\u2010olds from the Adolescent Brain and Cognitive Development (ABCD) Study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Using multilevel longitudinal linear modelling, we found greater discounting was associated with higher BMI Z\u2010scores (BMIz) and waist\u2010to\u2010height ratio Z\u2010scores (WHtRz) (<jats:italic>N<\/jats:italic>\u2009=\u20093819). Moreover, we observed functional connectivity of the nucleus accumbens to the cingulo\u2010opercular, dorsal attention, fronto\u2010parietal, salience and ventral attention networks were predictive of BMIz (<jats:italic>N<\/jats:italic>\u2009=\u20091817). Nucleus accumbens functional connectivity was not found to mediate the association between delay\u2010discounting behaviour and BMIz.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Delay discounting and nucleus accumbens functional connectivity are independently related to weight status in a large sample of early adolescents. A better understanding of the relationship between reward and overeating behaviours may better inform obesity interventions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijpo.13173","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T05:14:20Z","timestamp":1726636460000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Delay discounting and nucleus accumbens functional connectivity are related to weight status in adolescents from the <scp>ABCD<\/scp> study"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6260-2205","authenticated-orcid":false,"given":"L. 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