{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:24:07Z","timestamp":1772843047038,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["K24\u2010HD01357"],"award-info":[{"award-number":["K24\u2010HD01357"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01\u2010HD27503"],"award-info":[{"award-number":["R01\u2010HD27503"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR000005"],"award-info":[{"award-number":["UL1TR000005"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Obesity"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Relative fat mass (RFM) has been used to estimate whole\u2010body fat percentage (%BF). However, whether RFM can mirror abdominal adiposity is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>In youth, we examined if RFM reflects abdominal adiposity, if there are age\/race\/sex differences in the relationships between RFM and abdominal adiposity, and if our present\u2010youth\u2010cohort\u2010derived RFM (RFM\u2010Y) improves the prediction of %BF and abdominal adiposity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In 358 youth (aged 10\u201319\u2009years; 168 black\/198 white) with normal weight and overweight\/obesity (without secondary or syndromic obesity), visceral (VAT), subcutaneous (SAT) and total abdominal adipose tissue (TAT) were assessed by MRI\/CT and %BF with DXA. RFM was calculated for ages 10\u201314\u2009years as [74\u2009\u2212\u2009(22\u2009\u00d7\u2009height\/waist circumference [WC])\u2009+\u2009(5\u2009\u00d7\u2009sex)] and 15\u201319\u2009years as [64\u2009\u2212\u2009(20\u2009\u00d7\u2009height\/WC)\u2009+\u2009(12\u2009\u00d7\u2009sex)]; sex\u2009=\u20090 for boys, 1 for girls. To develop and validate RFM\u2010Y, linear regression, concordance correlation coefficient, Bland\u2013Altman plots and intraclass correlation coefficient were conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      RFM associated with VAT, SAT and TAT (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.66, 0.79, 0.79, respectively; all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The slope was significantly greater in (a) younger versus older youth for VAT, SAT and TAT; (b) whites versus blacks for VAT; and (c) girls versus boys for SAT and TAT. RFM\u2010Y versus traditional RFM showed improved predictive ability for %BF (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.83 vs. 0.77) and abdominal adiposity (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      ranging from 0.51 to 0.80 vs. 0.37 to 0.63).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>RFM reflects abdominal adiposity besides %BF and could be used in longitudinal\/interventional youth trials, obviating the need for expensive imaging to assess changes in total and abdominal adiposity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijpo.70059","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T08:15:24Z","timestamp":1760516124000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Relative Fat Mass as an Estimator of Abdominal Adiposity in Youth Across the\n                    <scp>BMI<\/scp>\n                    Spectrum from Normal Weight to Obesity"],"prefix":"10.1111","volume":"20","author":[{"given":"Wonhee","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Exercise Science, David B. Falk College of Sport Syracuse University  Syracuse New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joon Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Exercise Science, David B. Falk College of Sport Syracuse University  Syracuse New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silva","family":"Arslanian","sequence":"additional","affiliation":[{"name":"Center for Pediatric Research in Obesity and Metabolism and the Division of Pediatric Endocrinology, Diabetes and Metabolism University of Pittsburgh, School of Medicine, UPMC Children's Hospital of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-019-0176-8"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp2102062"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2022-057956"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2005.10.001"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.01.06.dc05-0952"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCO.0b013e32830b5f23"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2008.13"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-1334"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/72.3.694"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114508966095"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/63.1.4"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-29362-1"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-51701-z"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2010.10.010"},{"issue":"4","key":"e_1_2_9_16_1","first-page":"557","article-title":"Waist 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Dimorphism of Adipose Tissue Distribution Across the Lifespan: A Cross\u2010Sectional Whole\u2010Body Magnetic Resonance Imaging Study","volume":"6","author":"Shen W.","year":"2009","journal-title":"Nutrition and Metabolism"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2001.35"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/65.6.1703"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000569"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13293-018-0189-3"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803780"},{"issue":"6","key":"e_1_2_9_35_1","first-page":"443","article-title":"Body Fat Distribution in Pubertal Girls Quantified by Magnetic Resonance Imaging","volume":"16","author":"De Ridder C.","year":"1992","journal-title":"International Journal of Obesity and Related Metabolic Disorders: Journal of the International Association for the Study 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