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The impact of vertical sleeve gastrectomy (VSG) on fat distribution and cardiac morphology\/function in YO\u2010T2D is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate changes in body composition, abdominal and cardiac fat depots, and cardiometabolic health in adolescents with YO\u2010T2D undergoing VSG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Anthropometrics, labs and imaging were used to assess participants pre\u2010surgery and 3\u201312\u2009months post\u2010surgery. MRI quantified pericardial (PAT), epicardial (EAT), subcutaneous (SAT) and visceral adipose tissue (VAT), hepatic fat fraction (HFF) and cardiac morphology\/function. Mixed\u2010effects models assessed longitudinal changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      By 12\u2009months, weight decreased from 134.3\u2009\u00b1\u20095.1 to 103.3\u2009\u00b1\u20095.2\u2009kg, VAT 1943\u2009\u00b1\u2009148 to 1248\u2009\u00b1\u2009150\u2009cm\n                      <jats:sup>3<\/jats:sup>\n                      , HFF 23.2%\u2009\u00b1\u20092.3% to 5.3%\u2009\u00b1\u20092.3% and PAT and EAT by 27% and 33% (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). Homeostatic model assessment of insulin resistance (HOMA\u2010IR) improved (7.8\u2009\u00b1\u20091.2 to 1.7\u2009\u00b1\u20091.2 [\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01]). BMI, SAT, resting heart rate (RHR), left ventricular (LV) mass and cardiac output (CO) also decreased (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). VAT decreases correlated with decreases in HFF (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.70,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01), HOMA\u2010IR (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.60,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04) and CO (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.70,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03). HFF decreases correlated with decreases in BMI (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.70,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03), HOMA\u2010IR (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.90,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), RHR (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.90,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002), CO (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.80,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007) and LV mass (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.70,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>VSG reduces ectopic and regional fat and improves associated insulin sensitivity and cardiac health in adolescents with YO\u2010T2D.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijpo.70068","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T07:33:36Z","timestamp":1763451216000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>MRI<\/scp>\n                    Analysis of Cardiac Fat, Abdominal Adiposity and Cardiac Function After Vertical Sleeve Gastrectomy in Youth With Type 2 Diabetes"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2088-1370","authenticated-orcid":false,"given":"Tyler J.","family":"Dobbs","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus and Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linnea","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"Department of Bioengineering University of Colorado Anschutz Medical Campus and Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Houchun Harry","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Radiology Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kendall S.","family":"Hunter","sequence":"additional","affiliation":[{"name":"Department of Bioengineering University of Colorado Anschutz Medical Campus and Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus and Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorna","family":"Browne","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus and Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Winter","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus and Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie G.","family":"Cree","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus and Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Pyle","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Washington and Seattle Children's Hospital  Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan L.","family":"Hills\u2010Dunlap","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus and Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane E. 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