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We explored these associations from ages 9 to 12 amongst initially healthy weight youth.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n The analytic sample included 4161 youth (10\u2009586 observations across three assessments; all healthy weight at baseline; 50.7% female; 52% breastfed more than 6\u2009months) from the Adolescent Brain Cognitive Development (ABCD) Study. Linear mixed\u2010effects models examined breastfeeding \u00d7 age \u00d7 sex and breastfeeding \u00d7 puberty \u00d7 sex interactions on BMI trajectories (kg\/m\n 2<\/jats:sup>\n ). Logistic regression estimated the risk of unhealthy weight (BMI \u2265\u200985th percentile) by ages 11\u201312. All analyses were stratified by sex.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Three\u2010way interactions were not significant. Significant breastfeeding \u00d7 age interactions (\n \u03b2<\/jats:italic>\n \u2009=\u2009\u22120.005,\n p<\/jats:italic>\n \u2009<\u20090.001) indicated that breastfed youth exhibited lower BMI trajectories, particularly when breastfed for more than 6\u2009months (\n \u03b2<\/jats:italic>\n \u2009=\u2009\u22120.006,\n p<\/jats:italic>\n \u2009<\u20090.001). Significant breastfeeding \u00d7 puberty interactions showed lower BMI trajectories across pubertal stages amongst breastfed youth (\n \u03b2<\/jats:italic>\n \u2009=\u2009\u22120.06,\n p<\/jats:italic>\n \u2009=\u20090.017), observed only in boys and especially in those breastfed beyond 6\u2009months (\n \u03b2<\/jats:italic>\n \u2009=\u2009\u22120.11,\n p<\/jats:italic>\n \u2009=\u20090.005). Breastfeeding was associated with a reduced unhealthy weight risk at ages 11\u201312 (RR\u2009=\u20090.78,\n p<\/jats:italic>\n \u2009=\u20090.002), exclusively in boys and amongst those breastfed more than 6\u2009months (RR\u2009=\u20090.52,\n p<\/jats:italic>\n \u2009<\u20090.001). No associations were found in girls.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Amongst initially healthy weight youth, breastfeeding, especially beyond 6\u2009months, was associated with healthier BMI trajectories and lower unhealthy weight risk in boys. Although these sex\u2010specific patterns warrant further research, our findings suggest that the associations between breastfeeding and body weight development extend into adolescence.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ijpo.70082","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T03:54:28Z","timestamp":1767844468000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Longer Breastfeeding Is Associated With Healthier Body Mass Index Trajectories and Lower Risk of Overweight and Obesity in Youth Aged 9\u201312\u2009Years"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2910-9926","authenticated-orcid":false,"given":"Jonatan","family":"Ottino Gonz\u00e1lez","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Diabetes and Metabolism. 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