{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:00:24Z","timestamp":1789754424002,"version":"4.0.1"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T00:00:00Z","timestamp":1777766400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Obesity"],"published-print":{"date-parts":[[2026,5]]},"abstract":"ABSTRACT<\/jats:title>\n \n Introduction<\/jats:title>\n The clinical relevance of continuous glucose monitoring (CGM) metrics in adolescents with obesity remains uncertain, particularly in relation to obesity\u2010related metabolic comorbidities.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n In a pilot study, 39 adolescents with obesity (age 12.9\u2009\u00b1\u20092.9\u2009years); 29 boys; mean body mass index standard deviation score (BMI SDS; 2.25\u2009\u00b1\u20090.58) underwent 15\u2009days of CGM along with fasting plasma glucose, oral glucose tolerance testing (OGTT), glycated haemoglobin (HbA1c), and assessment of metabolic comorbidities.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Adolescents with metabolic dysfunction\u2013associated steatotic liver disease (MASLD;\n n<\/jats:italic>\n \u2009=\u20095, 12.8%) demonstrated higher median mean amplitude of glycaemic excursion (MAGE; 42.4 vs. 35.2\u2009mg\/dL;\n p<\/jats:italic>\n \u2009=\u20090.019) and mean of daily difference (MODD; 23.3 vs. 18.5\u2009mg\/dL;\n p<\/jats:italic>\n \u2009=\u20090.062) compared with those without it. BMI SDS correlated positively with glucose management indicator (GMI;\n \u03c1<\/jats:italic>\n \u2009=\u20090.34,\n p<\/jats:italic>\n \u2009=\u20090.041), mean glucose (\n \u03c1<\/jats:italic>\n \u2009=\u20090.34,\n p<\/jats:italic>\n \u2009=\u20090.041), and continuous overall net glycaemic action (CONGA;\n \u03c1<\/jats:italic>\n \u2009=\u20090.38,\n p<\/jats:italic>\n \u2009=\u20090.022), whereas fasting glucose, 2\u2010h OGTT glucose, and HbA1c showed no associations.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n In adolescents with obesity, CGM\u2010derived glycaemic variability metrics were associated with adiposity and MASLD, whereas conventional laboratory measures were not. These findings suggest that CGM may provide complementary information for metabolic phenotyping in paediatric obesity. Longitudinal studies are required to determine implications.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ijpo.70110","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:34:48Z","timestamp":1777862088000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Continuous Glucose Monitoring Metrics Are Associated With Metabolic Dysfunction\u2013Associated Steatotic Liver Disease and Not Dysglycaemia in Adolescents With Obesity\u2014A Pilot Study"],"prefix":"10.1111","volume":"21","author":[{"given":"Alapan","family":"Mahapatra","sequence":"first","affiliation":[{"name":"Department of Pediatric Endocrinology Regency Center for Diabetes, Endocrinology & Research Kanpur India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology Regency Center for Diabetes, Endocrinology & Research Kanpur India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vibha","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology Regency Center for Diabetes, Endocrinology & Research Kanpur India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Shukla","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology Regency Center for Diabetes, Endocrinology & Research Kanpur India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5785-5833","authenticated-orcid":false,"given":"Anoop","family":"Misra","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Metabolic Disorders Fortis\u2010C\u2010DOC Centre of Excellence for Diabetes, Metabolic Diseases and Endocrinology New Delhi 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