{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T17:49:26Z","timestamp":1788457766717,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T00:00:00Z","timestamp":1783209600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Obesity"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The national POWER registry of paediatric weight management programmes reported increased obesity medication (ObM) use in recent years. However, factors influencing ObM prescribing are not well understood. This study aimed to compare (1) clinical characteristics between youth prescribed ObMs and those who were not and (2) prescribing patterns among programmes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Data from youth aged 6\u201318\u2009years seen at 12 POWER sites between 2018 and 2024 were analysed. Clinical and demographic variables were compared between ObM and non\u2010ObM groups using Fisher's exact test and logistic regression, adjusting for site. Site\u2010level prescribing patterns were assessed using\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      and Fisher's exact tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>ObMs were prescribed to 927 of 4628 (20%) patients. Topiramate (37%) and metformin (43%) were the most prescribed. ObM patients were older [12\u201315\u2009years aOR (CI)\u2009=\u20091.7 (1.4, 2.0); 16\u201318\u2009years aOR (CI)\u2009=\u20091.6 (1.3, 2.0) vs. 6\u201311\u2009years], had more severe obesity [Class 2 aOR (CI)\u2009=\u20091.6 (1.3, 2.2); Class 3 aOR (CI)\u2009=\u20092.9 (2.3, 3.8) vs. Class 1] and had more obesity related co\u2010morbidities, but demographic characteristics were not different. Higher prescribing programmes offered ObMs sooner and multiple ObMs more often.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ObM prescribing was strongly associated with age, obesity severity and comorbidities, highlighting the need for prospective studies on earlier initiation to prevent disease progression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijpo.70127","type":"journal-article","created":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T01:14:36Z","timestamp":1783300476000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Correlates of Obesity Medication Use in Paediatric Weight Management Programmes: A\n                    <scp>POWER<\/scp>\n                    Consortium Analysis"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1836-0533","authenticated-orcid":false,"given":"Amy L.","family":"Christison","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Illinois College of Medicine at Peoria  Peoria Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Kim","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Children's Section for Pediatric Endocrinology  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen","family":"King","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"University of Cincinnati College of Medicine  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Sahay","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roohi","family":"Kharofa","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"University of Cincinnati College of Medicine  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooke R.","family":"Sweeney","sequence":"additional","affiliation":[{"name":"Children's Mercy Kansas City, Center for Children's Healthy Lifestyles &amp; Nutrition University of Missouri Kansas City  Kansas City Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3537-2782","authenticated-orcid":false,"given":"Vidhu","family":"Thaker","sequence":"additional","affiliation":[{"name":"Columbia U Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared M.","family":"Tucker","sequence":"additional","affiliation":[{"name":"Helen Devos Children's Hospital  Grand Rapids Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3790-6255","authenticated-orcid":false,"given":"Alaina P.","family":"Vidmar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Children's Hospital Los Angeles and Keck School of Medicine of USC, Center for Endocrinology, Diabetes and Metabolism  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2423-8318","authenticated-orcid":false,"given":"Jennifer K.","family":"Yee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Endocrinology the Lundquist Institute of Biomedical Innovation at Harbor\u2010UCLA Medical Center; David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelley","family":"Kirk","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"University of Cincinnati College of Medicine  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,5]]},"reference":[{"key":"e_1_2_14_2_1","volume-title":"National Health and Nutrition Examination Survey 2017\u2013March 2020 Prepandemic Data Files\u2014Development of Files and Prevalence Estimates for Selected Health Outcomes","author":"Stierman B.","year":"2021"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004\u20100229"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2022\u2010060643"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2022\u2010060640"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.0332"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.6739"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22385"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijpo.13113"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijpo.12701"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2208601"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1916038"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/evidoa2200014"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.11809"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/cen.15133"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.15473"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/2042018819863022"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijpo.12848"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1089\/chi.2023.0083"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.12.049"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1089\/chi.2016.0060"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28335"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7420a1"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.7112"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/20420188221090009"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.29422"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1017\/cts.2023.612"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.57232"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/cob.12577"}],"container-title":["Pediatric Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijpo.70127","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijpo.70127","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijpo.70127","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:16:46Z","timestamp":1785370606000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijpo.70127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":28,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/ijpo.70127"],"URL":"https:\/\/doi.org\/10.1111\/ijpo.70127","archive":["Portico"],"relation":{},"ISSN":["2047-6302","2047-6310"],"issn-type":[{"value":"2047-6302","type":"print"},{"value":"2047-6310","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2025-10-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70127"}}