{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T23:18:52Z","timestamp":1787872732770,"version":"build-2784847793"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["ZIAHD000641"],"award-info":[{"award-number":["ZIAHD000641"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["ZIAHD009004\u201001656312"],"award-info":[{"award-number":["ZIAHD009004\u201001656312"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["#731903"],"award-info":[{"award-number":["#731903"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["ZIADK075133"],"award-info":[{"award-number":["ZIADK075133"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["ZICDK071013"],"award-info":[{"award-number":["ZICDK071013"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Obesity"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In adolescents with obesity \u2265\u20091\u2010year post\u2010vertical sleeve gastrectomy (VSG), a pilot trial of liraglutide demonstrated a 4.3% BMI reduction. This secondary analysis evaluated energy intake changes (\u2206EI) and associations of \u2206EI with oral glucose tolerance test (OGTT) outcomes and end\u2010of\u2010trial liraglutide plasma concentrations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>At baseline and after 4\u2009months of liraglutide, participants completed a standardised buffet meal following a 2\u2010h OGTT. Liraglutide plasma area under the curves (AUCs) were quantified using LC\u2013MS\/MS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010seven participants (18.1\u2009\u00b1\u20092.0\u2009years; BMI: 40.4\u2009\u00b1\u20097.3\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ) completed buffet meals at both visits. Mean energy intake decreased by 161.7\u2009\u00b1\u2009264.3\u2009kcal (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04) and food mass by 72.5\u2009\u00b1\u2009123.4\u2009g (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02), with proportional reductions in absolute macronutrient intake but no change in macronutrient distribution. Neither Liraglutide AUC (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200917) nor OGTT outcomes were significantly associated with \u2206EI or changes in body weight.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In adolescents post\u2010VSG treated with liraglutide, overall food intake decreased without significant changes in macronutrient composition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijpo.70140","type":"journal-article","created":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T04:55:58Z","timestamp":1785560158000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Liraglutide on Energy Intake in Adolescents With\u00a0Persistent Obesity After Vertical Sleeve Gastrectomy"],"prefix":"10.1111","volume":"21","author":[{"given":"Bao\u2010Vi C.","family":"Tran","sequence":"first","affiliation":[{"name":"Section on Growth and Obesity, DIR Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7502-6422","authenticated-orcid":false,"given":"Anna","family":"Zenno","sequence":"additional","affiliation":[{"name":"Section on Growth and Obesity, DIR Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazrat M.","family":"Mirza","sequence":"additional","affiliation":[{"name":"Children's National Hospital  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8312-4647","authenticated-orcid":false,"given":"Evan","family":"Nadler","sequence":"additional","affiliation":[{"name":"Children's National Hospital  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila M.","family":"Brady","sequence":"additional","affiliation":[{"name":"Section on Growth and Obesity, DIR Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otiti A.","family":"Mayo","sequence":"additional","affiliation":[{"name":"Section on Growth and Obesity, DIR Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2861-814X","authenticated-orcid":false,"given":"Alexa P.","family":"Lyman","sequence":"additional","affiliation":[{"name":"Section on Growth and Obesity, DIR Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6989-0417","authenticated-orcid":false,"given":"Stephanie T.","family":"Chung","sequence":"additional","affiliation":[{"name":"National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0306-1904","authenticated-orcid":false,"given":"Kong Y.","family":"Chen","sequence":"additional","affiliation":[{"name":"National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Walter","sequence":"additional","affiliation":[{"name":"National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyi","family":"Cai","sequence":"additional","affiliation":[{"name":"National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanna B.","family":"Yang","sequence":"additional","affiliation":[{"name":"Nutrition Department, Clinical Center National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6679-8876","authenticated-orcid":false,"given":"Sara 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