{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:58:30Z","timestamp":1790319510199,"version":"4.1.0"},"reference-count":43,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Obesity"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The thermic effect of food (TEF) represents an important but often overlooked component of total energy expenditure. The effects of meals with varying energy content but identical macronutrient distribution on TEF are unclear in adolescents with obesity. This study examined the effects of increasing meal energy on TEF, appetite, and food reward. Fifteen adolescents with obesity completed a randomized crossover trial with three lunch test meals (700, 1000, 1300\u2009kcal) matched for macronutrient distribution. Postprandial energy expenditure was measured over 5 h to assess TEF, while appetite and food reward were assessed using visual analog scales and the Leeds Food Preference Questionnaire, respectively. TEF differed by meal size (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), with the 1300\u2010kcal meal eliciting a greater TEF than the 700\u2010kcal meal (\u03b2\u2009=\u20090.12\u2009kcal\u00b7min\n                    <jats:sup>\u22121<\/jats:sup>\n                    , 95% CI [0.06, 0.18],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Differences between the 700\u2010 and 1000\u2010kcal meals were not significant, and the 1000\u2010 versus 1300\u2010kcal comparison showed a trend toward significance. Relative TEF (% of meal energy) did not differ between meals. Appetite ratings were unaffected by meal size. Food reward measures were largely unaffected by meal condition, with isolated differences in sweet appeal bias and explicit liking for high\u2010fat sweet foods. In adolescents with obesity, TEF increases only with large differences in meal energy and remains proportional to energy intake. Together, the stable TEF and the absence of differences in appetite or food reward suggest that larger meals may not promote greater satiety, potentially favouring higher daily energy intake relative to energy expenditure.\n                  <\/jats:p>","DOI":"10.1111\/ijpo.70155","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:34:28Z","timestamp":1790127268000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Meal Caloric Content on the Thermic Effect of Food in Adolescents With Obesity"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-1557-2737","authenticated-orcid":false,"given":"N.","family":"Beauregard","sequence":"first","affiliation":[{"name":"Laboratory of the Metabolic Adaptations to Exercise Under Physiological and Pathological Conditions (AME2P), Centre de Recherche en Nutrition Humaine Clermont Auvergne University  Clermont\u2010Ferrand France"},{"name":"School of Human Kinetics University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2821-3206","authenticated-orcid":false,"given":"E.","family":"Doucet","sequence":"additional","affiliation":[{"name":"School of Human Kinetics University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Gad\u00e9a","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Recherche Clinique Centre Hospitalier Emile Roux  Le Puy en Velay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5620-2256","authenticated-orcid":false,"given":"G.","family":"Finlayson","sequence":"additional","affiliation":[{"name":"Appetite Control &amp; Energy Balance Research Group, School of Psychology, Faculty of Medicine &amp; Health University of Leeds  Leeds West Yorkshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Beraud","sequence":"additional","affiliation":[{"name":"Laboratory of the Metabolic Adaptations to Exercise Under Physiological and Pathological Conditions (AME2P), Centre de Recherche en Nutrition Humaine Clermont Auvergne University  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8493-1782","authenticated-orcid":false,"given":"J.","family":"Siroux","sequence":"additional","affiliation":[{"name":"Laboratory of the Metabolic Adaptations to Exercise Under Physiological and Pathological Conditions (AME2P), Centre de Recherche en Nutrition Humaine Clermont Auvergne University  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4776-4090","authenticated-orcid":false,"given":"S.","family":"Cournier","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Recherche Clinique Centre Hospitalier Emile Roux  Le Puy en Velay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Masurier","sequence":"additional","affiliation":[{"name":"SSR Obesit\u00e9 Nutrition UGECAM  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3778-7161","authenticated-orcid":false,"given":"B.","family":"Pereira","sequence":"additional","affiliation":[{"name":"Biostatistics Unit, DRCI, CHU Clermont\u2010Ferrand  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3999-1599","authenticated-orcid":false,"given":"Y.","family":"Boirie","sequence":"additional","affiliation":[{"name":"Department of Human Nutrition CHU Clermont\u2010Ferrand  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1152-3902","authenticated-orcid":false,"given":"L.","family":"Isacco","sequence":"additional","affiliation":[{"name":"Laboratory of the Metabolic Adaptations to Exercise Under Physiological and Pathological Conditions (AME2P), Centre de Recherche en Nutrition Humaine Clermont Auvergne University  Clermont\u2010Ferrand France"},{"name":"International Research Chair Health in Motion Clermont Auvergne University Foundation  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4687-3555","authenticated-orcid":false,"given":"D.","family":"Thivel","sequence":"additional","affiliation":[{"name":"Laboratory of the Metabolic Adaptations to Exercise Under Physiological and Pathological Conditions (AME2P), Centre de Recherche en Nutrition Humaine Clermont Auvergne University  Clermont\u2010Ferrand 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