{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T02:23:17Z","timestamp":1767838997110,"version":"3.49.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T00:00:00Z","timestamp":1363824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Stroke"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> The cause of perimesencephalic hemorrhage is unknown, but a venous source is suggested. If perimesencephalic hemorrhage is of venous origin, less elevation of the intracranial pressure and less perfusion deficits are expected than after aneurysmal subarachnoid hemorrhage. <\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p> We compared perfusion in the acute stage after perimesencephalic hemorrhage and aneurysmal subarachnoid hemorrhage. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> We included 45 perimesencephalic hemorrhage patients and 45 aneurysmal subarachnoid hemorrhage patients, who were matched on clinical condition at admission and underwent computerized tomographic scanning &lt;72 h after subarachnoid hemorrhage. Cerebral blood flow was assessed in 12 predefined regions of interest. Differences in cerebral blood flow values with corresponding 95% confidence intervals were calculated. Sub-group analyses were performed stratified on comparable amounts of blood and location of blood (posterior circulation aneurysms and additionally in infratentorial and supratentorial aneurysms). <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Cerebral blood flow was higher in perimesencephalic hemorrhage patients (mean: 63\u00b78) than in aneurysmal subarachnoid hemorrhage patients (mean: 55\u00b79; difference of means: \u22127\u00b79 [95% confidence interval: \u221210\u00b77 to \u22125\u00b72]) and also in the sub-group with comparable amounts of blood (mean cerebral blood flow: 56\u00b74; difference of means: \u22127\u00b74 [95% confidence interval: \u221210\u00b74 to \u22124\u00b73]). Cerebral blood flow was comparable with perimesencephalic hemorrhage patients for the sub-group with posterior circulation aneurysms (difference of means: \u22120\u00b77 [95% confidence interval: \u22125\u00b72 to 3\u00b78]); however, differences diverged after stratifying posterior circulation aneurysms into supratentorial (difference of means \u22123\u00b79 [95% confidence interval: \u22129\u00b73 to 1\u00b74]) and infratentorial aneurysms (difference of means 3\u00b70 [95% confidence interval: \u22122\u00b78 to 8\u00b78]). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> Perimesencephalic hemorrhage patients have a higher cerebral blood flow than aneurysmal subarachnoid hemorrhage patients. The findings of this study further support a venous origin of bleeding in perimesencephalic hemorrhage patients. Future studies should further elaborate on cerebral blood flow in posterior circulation aneurysms. <\/jats:p><\/jats:sec>","DOI":"10.1111\/ijs.12021","type":"journal-article","created":{"date-parts":[[2013,3,23]],"date-time":"2013-03-23T06:18:32Z","timestamp":1364019512000},"page":"183-187","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Cerebral CT Perfusion in Patients with Perimesencephalic and Those with Aneurysmal Subarachnoid Hemorrhage"],"prefix":"10.1177","volume":"9","author":[{"given":"Charlotte H. P.","family":"Cremers","sequence":"first","affiliation":[{"name":"Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene C.","family":"van der Schaaf","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Willem","family":"Dankbaar","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgitta K.","family":"Velthuis","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel J. E.","family":"Rinkel","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,3,21]]},"reference":[{"key":"bibr1-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2005.07.004"},{"key":"bibr2-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.35.4.493"},{"key":"bibr3-ijs.12021","first-page":"829","volume":"12","author":"Rinkel GJ","year":"1991","journal-title":"AJNR Am J Neuroradiol"},{"key":"bibr4-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-001-0741-3"},{"key":"bibr5-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000131657.08655.ce"},{"key":"bibr6-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198804000-00006"},{"key":"bibr7-ijs.12021","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1985.62.6.0850"},{"key":"bibr8-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2009.0924"},{"key":"bibr9-ijs.12021","first-page":"985","volume":"68","author":"Drake CG","year":"1988","journal-title":"J Neurosurg"},{"key":"bibr10-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.21.8.1156"},{"key":"bibr11-ijs.12021","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1985.63.3.0355"},{"key":"bibr12-ijs.12021","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1748"},{"key":"bibr13-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2313021488"},{"key":"bibr14-ijs.12021","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1972.37.3.0302"},{"key":"bibr15-ijs.12021","first-page":"142","volume":"98","author":"Petruk KC","year":"1973","journal-title":"Trans Am Neurol Assoc"},{"key":"bibr16-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1007\/s007010050318"},{"key":"bibr17-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199802000-00091"},{"key":"bibr18-ijs.12021","doi-asserted-by":"publisher","DOI":"10.3171\/2008.8.JNS08591"},{"key":"bibr19-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.1986.12"},{"key":"bibr20-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.7.855"},{"key":"bibr21-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1097\/00006231-200107000-00003"},{"key":"bibr22-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.209.3.9844657"},{"key":"bibr23-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-003-1132-8"},{"key":"bibr24-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198301000-00010"},{"key":"bibr25-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000064840.99271.9E"},{"key":"bibr26-ijs.12021","first-page":"905","volume":"22","author":"Wintermark M","year":"2001","journal-title":"AJNR Am J Neuroradiol"},{"key":"bibr27-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2003.00174.x"},{"key":"bibr28-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000148902.61943.DF"},{"key":"bibr29-ijs.12021","first-page":"46","volume":"27","author":"Van der Schaaf I","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"bibr30-ijs.12021","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2312030489"}],"container-title":["International Journal of Stroke"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijs.12021","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1111\/ijs.12021","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1111\/ijs.12021","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1111\/ijs.12021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T05:44:03Z","timestamp":1741671843000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1111\/ijs.12021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,21]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1111\/ijs.12021"],"URL":"https:\/\/doi.org\/10.1111\/ijs.12021","relation":{},"ISSN":["1747-4930","1747-4949"],"issn-type":[{"value":"1747-4930","type":"print"},{"value":"1747-4949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,21]]}}}