{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T16:09:34Z","timestamp":1783181374067,"version":"3.54.6"},"reference-count":10,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T00:00:00Z","timestamp":1428278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Stroke"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> The location of plaque may be associated with the vascular geometry. <\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p> We aimed to examine the relationship between the geometry of middle cerebral artery and the plaque location detected by high-resolution magnetic resonance imaging. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> Among patients with a single subcortical infarction without a significant middle cerebral artery stenosis on magnetic resonance angiography, those with a plaque detected from high-resolution magnetic resonance imaging were prospectively enrolled. The shape of middle cerebral artery was measured from the coronal view, and was classified as straight, U-shaped, inverted U-shaped, and S-shaped. The location of the plaque was divided into superior and inferior, and analyzed according to the shape of middle cerebral artery. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Among the 40 patients, the shape of middle cerebral artery was straight in 7 (17\u00b75%), U-shaped in 10 (15\u00b70%), inverted U-shaped in 11 (27\u00b75%), and S-shaped in 12 patients (30\u00b70%). The superior plaque was more closely associated with straight (85\u00b77%) or U-shaped middle cerebral arteries (90\u00b70%), whereas inverted U-shaped (81\u00b78%) and S-shaped middle cerebral arteries (75\u00b70%) were more often associated with inferior plaque. The prevalence of symptomatic plaque was higher in superior than inferior plaques (70\u00b70% vs. 25\u00b70%, P = 0\u00b7004). Multivariate analysis showed that straight and U-shaped middle cerebral artery was the only significant factor associated with the superior plaque. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> The shape of middle cerebral artery may be a factor determining the location of early atherosclerotic plaque. <\/jats:p><\/jats:sec>","DOI":"10.1111\/ijs.12497","type":"journal-article","created":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T07:48:55Z","timestamp":1428306535000},"page":"856-860","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":42,"title":["The Shape of Middle Cerebral Artery and Plaque Location: High-Resolution MRI Finding"],"prefix":"10.1177","volume":"10","author":[{"given":"Bum Joon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Ulsan, Asan Medical Center, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youngshin","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Ulsan, Asan Medical Center, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deok-Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University of Ulsan, Asan Medical Center, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Wha","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Ulsan, Asan Medical Center, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun U.","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Ulsan, Asan Medical Center, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong S.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Ulsan, Asan Medical Center, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,4,6]]},"reference":[{"key":"bibr1-ijs.12497","doi-asserted-by":"publisher","DOI":"10.5853\/jos.2014.16.1.27"},{"key":"bibr2-ijs.12497","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000225074.47396.71"},{"key":"bibr3-ijs.12497","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001467"},{"key":"bibr4-ijs.12497","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.21.2035"},{"key":"bibr5-ijs.12497","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.645499"},{"key":"bibr6-ijs.12497","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.110.958504"},{"key":"bibr7-ijs.12497","doi-asserted-by":"publisher","DOI":"10.1159\/000076124"},{"key":"bibr8-ijs.12497","doi-asserted-by":"publisher","DOI":"10.1038\/nature03952"},{"key":"bibr9-ijs.12497","doi-asserted-by":"publisher","DOI":"10.1114\/1.113"},{"key":"bibr10-ijs.12497","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.15.7.912"}],"container-title":["International Journal of Stroke"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijs.12497","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1111\/ijs.12497","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1111\/ijs.12497","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1111\/ijs.12497","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T04:27:02Z","timestamp":1741667222000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1111\/ijs.12497"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,6]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1111\/ijs.12497"],"URL":"https:\/\/doi.org\/10.1111\/ijs.12497","relation":{},"ISSN":["1747-4930","1747-4949"],"issn-type":[{"value":"1747-4930","type":"print"},{"value":"1747-4949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,6]]}}}