{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T01:21:42Z","timestamp":1789953702638,"version":"4.0.1"},"reference-count":10,"publisher":"SAGE Publications","issue":"SA100","license":[{"start":{"date-parts":[[2015,9,9]],"date-time":"2015-09-09T00:00:00Z","timestamp":1441756800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"NIH","award":["P50-NS049060"],"award-info":[{"award-number":["P50-NS049060"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Stroke"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec><jats:title>Rationale<\/jats:title><jats:p> Stroke and vascular risk factors disproportionately affect minority populations, with Blacks and Hispanics experiencing a 2.5- and 2.0-fold greater risk compared with whites, respectively. Patients with transient ischemic attacks and mild, nondisabling strokes tend to have short hospital stays, rapid discharges, and inaccurate perceptions of vascular risk. <\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p> The primary aim of the Discharge Educational Strategies for Reduction of Vascular Events (DESERVE) trial is to evaluate the efficacy of a novel community health worker-based multilevel discharge intervention vs. standard discharge care on vascular risk reduction among racially\/ethnically diverse transient ischemic attack\/mild stroke patients at one-year postdischarge. We hypothesize that those randomized to the discharge intervention will have reduced modifiable vascular risk factors as determined by systolic blood pressure compared with those receiving usual care. <\/jats:p><\/jats:sec><jats:sec><jats:title>Sample size estimates<\/jats:title><jats:p> Given 300 subjects per group and alpha of 0.05, the power to detect a 6 mmHg reduction in systolic blood pressure is 89%. <\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p> DESERVE trial is a prospective, randomized, multicenter clinical trial of a novel discharge behavioral intervention. Patients with transient ischemic attack\/mild stroke are randomized during hospitalization or emergency room visit to intervention or usual care. Intervention begins prior to discharge and continues postdischarge. <\/jats:p><\/jats:sec><jats:sec><jats:title>Study outcomes<\/jats:title><jats:p> The primary outcome is difference in systolic blood pressure reduction between groups at 12 months. Secondary outcomes include between-group differences in change in glycated hemoglobin, smoking rates, medication adherence, and recurrent stroke\/transient ischemic attack at 12 months. <\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p> DESERVE will evaluate whether a novel discharge education strategy leads to improved risk factor control in a racially diverse population. <\/jats:p><\/jats:sec>","DOI":"10.1111\/ijs.12571","type":"journal-article","created":{"date-parts":[[2015,9,10]],"date-time":"2015-09-10T11:42:08Z","timestamp":1441885328000},"page":"151-154","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Discharge educational strategies for reduction of vascular events (DESERVE): design and methods"],"prefix":"10.1177","volume":"10","author":[{"given":"Aaron S.","family":"Lord","sequence":"first","affiliation":[{"name":"Department of Neurology, New York University School 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette","family":"Boden-Albala","sequence":"additional","affiliation":[{"name":"Department of Neurology, New York University School of Medicine, New York, NY, USA"},{"name":"Division of Social Epidemiology, College of Global Public Health, New York University, New York, NY, USA"},{"name":"Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, NY, 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