{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:14:03Z","timestamp":1790255643233,"version":"4.1.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"SA100","license":[{"start":{"date-parts":[[2015,8,26]],"date-time":"2015-08-26T00:00:00Z","timestamp":1440547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100004748","name":"Mashhad University of Medical Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004748","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Stroke"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> In developing countries, there are few comprehensive studies of mortality following stroke. <\/jats:p><\/jats:sec><jats:sec><jats:title>Aims and\/or hypothesis<\/jats:title><jats:p> We aimed to determine the one-year case fatality rate following stroke and to identify factors associated with death in a population-based stroke incidence study in Iran. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> Six hundred eighty-four patients who had suffered a stroke between November 21, 2006, and November 20, 2007, and were recruited to the Mashhad Stroke Incidence Study were followed up at one-year. Most patients were seen in an outpatient visit. When patients had died, a verbal autopsy was conducted by telephone with the next of kin. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> A total of 226 (34.3%) patients died during the first year following stroke. The cumulative one-year case fatality rate was 30.6% following ischemic stroke and 53.0% following hemorrhagic stroke (55.8% after intracerebral hemorrhage and 35.7% after subarachnoid hemorrhage). The majority of these deaths occurred in the first 28 days after stroke (17.7% with ischemic and 43.0% with hemorrhagic stroke). Factors associated with greater mortality at one-year (excluding those who died during the first week) were hemorrhagic stroke [hazard ratio (HR) 3.99; 95% confidence interval 1.90-8.37], age (HR 1.05; 95% confidence interval 1.03-1.08), previous transient ischemic attack (HR 2.45; 95% confidence interval 1.00-5.99), and National Institutes of Health Stroke Scale on admission (HR 1.14; 95% confidence interval 1.10-1.17). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> Despite the younger age of stroke occurrence in Iran, the one-year case fatality rate following stroke is similar to that reported in developed countries. <\/jats:p><\/jats:sec>","DOI":"10.1111\/ijs.12611","type":"journal-article","created":{"date-parts":[[2015,8,26]],"date-time":"2015-08-26T08:33:31Z","timestamp":1440578011000},"page":"96-102","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["One-year case fatality rate following stroke in the Mashhad Stroke Incidence Study: a population-based study of stroke in Iran"],"prefix":"10.1177","volume":"10","author":[{"given":"Ali","family":"Shoeibi","sequence":"first","affiliation":[{"name":"School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Salehi","sequence":"additional","affiliation":[{"name":"Departments of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"},{"name":"Research Center for Patient Safety, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda G.","family":"Thrift","sequence":"additional","affiliation":[{"name":"Stroke and Ageing Research, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia"},{"name":"Stroke Division, the Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moira K.","family":"Kapral","sequence":"additional","affiliation":[{"name":"Medicine and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada"},{"name":"Institute for Clinical Evaluative Sciences and Toronto General Research Institute, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Taghi","family":"Farzadfard","sequence":"additional","affiliation":[{"name":"School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Azarpazhooh","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry and Institute of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parvaneh","family":"Layegh","sequence":"additional","affiliation":[{"name":"School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peyman","family":"Hashemi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amin","family":"Amiri","sequence":"additional","affiliation":[{"name":"Department of Neurology, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naghmeh","family":"Mokhber","sequence":"additional","affiliation":[{"name":"School of Medicine, Department of the Elderly, Ave Sina Hospital, Mashhad University of Medical Sciences, Mashhad, Iran"},{"name":"Psychiatry and Behavioural Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahare","family":"Hassankhani","sequence":"additional","affiliation":[{"name":"School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud Reza","family":"Azarpazhooh","sequence":"additional","affiliation":[{"name":"School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"},{"name":"London Health Science Center, London, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,8,26]]},"reference":[{"key":"bibr1-ijs.12611","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61728-0"},{"key":"bibr2-ijs.12611","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70031-5"},{"key":"bibr3-ijs.12611","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61953-4"},{"key":"bibr4-ijs.12611","doi-asserted-by":"publisher","DOI":"10.1159\/000264827"},{"key":"bibr5-ijs.12611","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.559708"},{"key":"bibr6-ijs.12611","first-page":"541","volume":"54","author":"Hatano S","year":"1976","journal-title":"Bull World Health 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