{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T10:32:03Z","timestamp":1780569123949,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,1,8]],"date-time":"2013-01-08T00:00:00Z","timestamp":1357603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Previous reports have suggested that the incidence of spina bifida occulta in patients with nocturnal enuresis is higher than in the general population. However, the effect of spina bifida occulta on the response to nocturnal enuresis treatment is controversial. The purpose of this study was to investigate the relationship between spina bifida occulta and response to treatment of nocturnal enuresis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 2006 and 2009, the records of 160 children with nocturnal enuresis were reviewed. Children with other organic urological disease or symptoms suggestive of spinal dysraphism were excluded. Plain radiography for the kidney\u2013ureter\u2013bladder was carried out before the start of the nocturnal enuresis treatment. Response to treatment of children with and without spina bifida occulta was compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 160 children, 53 were girls; the mean age was 7.8\u2009\u00b1\u20092.06 years. The mean duration of treatment was 8.7\u2009\u00b1\u20099.29 months. Spina bifida occulta was detected in 43 children (26.9%). Spina bifida occulta affected <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>4 in four children, <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>5 in 12 children, <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>1 in 26 children and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>2 in one child. There was a significant difference between the spina bifida occulta and non\u2010spina bifida occulta groups in terms of outcome (<jats:italic>P<\/jats:italic>\u2009=\u20090.002), with a complete response more likely in children without spina bifida occulta (<jats:italic>P<\/jats:italic>\u2009=\u20090.005). None of the children with primary non\u2010mono symptomatic nocturnal enuresis and spina bifida occulta showed a complete response.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The presence of spina bifida occulta significantly affects the response to treatment in patients with nocturnal enuresis. Thus, verifying spina bifida occulta in this patient population can facilitate the prediction of the response to nocturnal enuresis treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.12054","type":"journal-article","created":{"date-parts":[[2013,1,8]],"date-time":"2013-01-08T23:57:04Z","timestamp":1357689424000},"page":"831-835","source":"Crossref","is-referenced-by-count":17,"title":["Spina bifida occulta: Not to be overlooked in children with nocturnal enuresis"],"prefix":"10.1111","volume":"20","author":[{"given":"Sang Hee","family":"Shin","sequence":"first","affiliation":[{"name":"Bladder\u2010Urethra Rehabilitation Clinic Yonsei University Health System  Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Jae","family":"Im","sequence":"additional","affiliation":[{"name":"Department of Urology Urological Science Institute Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi\u2010Jung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology Research Institute of Radiological Science Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Seung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Urological Science Institute Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Kyoung","family":"Choi","sequence":"additional","affiliation":[{"name":"Bladder\u2010Urethra Rehabilitation Clinic Yonsei University Health System  Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Won","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Urology Urological Science Institute Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)32718-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(85)80100-8"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.20367"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1985.tb06410.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.298.6670.357"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)39481-8"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000110633.88479.3f"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3171\/PED\/2008\/1\/2\/114"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02859261"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2006.01666.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.10.043"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2010.04.014"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-3691"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-002-0861-x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2012.13.5.610"}],"container-title":["International Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fiju.12054","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iju.12054","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T10:22:15Z","timestamp":1696328535000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iju.12054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,8]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/iju.12054"],"URL":"https:\/\/doi.org\/10.1111\/iju.12054","archive":["Portico"],"relation":{},"ISSN":["0919-8172","1442-2042"],"issn-type":[{"value":"0919-8172","type":"print"},{"value":"1442-2042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,8]]}}}