{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T10:37:54Z","timestamp":1776422274321,"version":"3.51.2"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the incidence, and clinical and bacterial features of iatrogenic prostatitis within 1 month after transrectal ultrasound\u2010guided biopsy for detection of prostate cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2006 to <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2009, 3000 patients underwent a 21\u2010core transrectal ultrasound\u2010guided prostate biopsy at Henri Mondor Hospital (Cr\u00e9teil, France) and were prospectively followed. All patients had a fluoroquinolone antimicrobial prophylaxis for 7 days. The primary study end\u2010point was to evaluate the incidence of iatrogenic acute prostatitis within 1 month after the biopsy. The secondary end\u2010point was to analyze the clinical and the bacterial features of the prostatitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 20 patients of the entire study population (0.67%) had an acute bacterial prostatitis within 2.90\u2009\u00b1\u20091.77 days (range 1\u20137 days) after the transrectal ultrasound\u2010guided biopsy. The groups of patients with (<jats:italic>n<\/jats:italic>\u2009=\u200920) and without (<jats:italic>n<\/jats:italic>\u2009=\u20092980) infection were similar in terms of age, prostate\u2010specific antigen level and prostate volume. <jats:italic>Escherichia coli<\/jats:italic> was the only isolated bacteria. The subsequent tests for antibiotic susceptibility showed a 95% resistance for fluroquinolone and amoxicillin. Resistance to amoxiclav, trimethoprim\u2010sulfamethoxazole, third generation cephalosporin and amikacin was 70%, 70%, 25% and 5% respectively. No resistance to imipenem was reported. They were all admitted for treatment without the need of intensive care unit referral. Complete recovery was achieved after 21.4\u2009\u00b1\u20097 days of antibiotic treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A fluroquinolone\u2010based regimen still represents an appropriate prophylaxis protocol to minimize the risk of acute prostatitis secondary to prostate biopsy. Patients should be provided the appropriate care soon after the onset of the symptoms. An intravenous third generation cephalosporin or imipenem\u2010based therapy seem to provide satisfying results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.12207","type":"journal-article","created":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T11:13:19Z","timestamp":1375355599000},"page":"152-155","source":"Crossref","is-referenced-by-count":31,"title":["Acute bacterial prostatitis after transrectal ultrasound\u2010guided prostate biopsy: Epidemiological, bacteria and treatment patterns from a 4\u2010year prospective study"],"prefix":"10.1111","volume":"21","author":[{"given":"Alexandre","family":"Campeggi","sequence":"first","affiliation":[{"name":"Department of Urology Henri Mondor Hospital AP\u2010HP Paris\u2010Est University  Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Idir","family":"Ouzaid","sequence":"additional","affiliation":[{"name":"Department of Urology Henri Mondor Hospital AP\u2010HP Paris\u2010Est University  Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evanguelos","family":"Xylinas","sequence":"additional","affiliation":[{"name":"Department of Urology Henri Mondor Hospital AP\u2010HP Paris\u2010Est University  Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Lesprit","sequence":"additional","affiliation":[{"name":"Department of Infection Prevention Unit Henri Mondor Hospital AP\u2010HP Paris\u2010Est University  Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andras","family":"Hoznek","sequence":"additional","affiliation":[{"name":"Department of Urology Henri Mondor Hospital AP\u2010HP Paris\u2010Est University  Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitri","family":"Vordos","sequence":"additional","affiliation":[{"name":"Department of Urology Henri Mondor Hospital AP\u2010HP Paris\u2010Est University  Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claude\u2010Cl\u00e9ment","family":"Abbou","sequence":"additional","affiliation":[{"name":"Department of Urology Henri Mondor Hospital AP\u2010HP Paris\u2010Est University  Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Salomon","sequence":"additional","affiliation":[{"name":"Department of Urology Henri Mondor Hospital AP\u2010HP Paris\u2010Est University  Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"de la Taille","sequence":"additional","affiliation":[{"name":"Department of Urology Henri Mondor Hospital AP\u2010HP Paris\u2010Est University  Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.10.039"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000061280.23447.29"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10561.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2004.09.015"},{"issue":"4","key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/1120009X.2000.11782309","article-title":"Fluoroquinolone pharmacodynamics: prospective determination of relationships between exposure and outcome","volume":"12","author":"Drusano GL","year":"2000","journal-title":"J Chemother."},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64565-X"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2000.00576.x"},{"key":"e_1_2_7_9_1","first-page":"163","article-title":"Giant septal cavity due to coronary artery fistula and ventricular septal dissection after cardiac surgery","volume":"9","author":"Branco LM","year":"2008","journal-title":"Eur. 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