{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T23:41:57Z","timestamp":1769125317030,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2014,5,7]],"date-time":"2014-05-07T00:00:00Z","timestamp":1399420800000},"content-version":"vor","delay-in-days":36,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy and safety of augmentation ileocystoplasty with supratrigonal cystectomy for the treatment of refractory bladder pain syndrome\/interstitial cystitis patients with Hunner's lesion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Of 45 patients who underwent augmentation ileocystoplasty with supratrigonal cystectomy between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>uly 2006 and <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>une 2012, 40 patients (33 women, 7 men) were included in the analysis. Primary outcome was the change in the <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>'Leary\u2013Sant interstitial cystitis symptoms\/problem index from baseline to 1, 3 and 6\u2009months. Changes in pain, urgency, frequency, functional bladder capacity and maximal cystometric capacity were also assessed. Intraoperative and postoperative complications were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median preoperative symptom duration was 5.0\u2009years (range 3.0\u20136.0\u2009years). Pain decreased significantly after surgery (8.3 <jats:italic>vs<\/jats:italic> 1.3, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Functional bladder capacity and maximal cystometric capacity increased, whereas frequency, urgency and nocturia decreased significantly after surgery (all <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). At 6\u2009months, significant improvements in the interstitial cystitis symptom index (17.8 <jats:italic>vs<\/jats:italic> 9.9, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and interstitial cystitis problem index (14.6 <jats:italic>vs<\/jats:italic> 6.5, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) compared with baseline were noted. Seven patients developed vesicoureteral reflux and seven patients had acute pyelonephritis that resolved with antibiotic treatment. Five patients required clean intermittent self\u2010catheterization. None of the preoperative factors were significant predictors of treatment failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Augmentation ileocystoplasty with supratrigonal cystecomy decreased pain and frequency, and increased bladder capacity significantly. There were no severe complications related to surgery during follow up. Augmentation ileocystoplasty with supratrigonal cystectomy is therefore an appropriate final treatment strategy for refractory bladder pain syndrome\/interstitial cystitis patients with <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>unner's lesion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.12320","type":"journal-article","created":{"date-parts":[[2014,5,8]],"date-time":"2014-05-08T02:46:29Z","timestamp":1399517189000},"page":"69-73","source":"Crossref","is-referenced-by-count":38,"title":["Efficacy and safety of augmentation ileocystoplasty combined with supratrigonal cystectomy for the treatment of refractory bladder pain syndrome\/interstitial cystitis with <scp>H<\/scp>unner's lesion"],"prefix":"10.1111","volume":"21","author":[{"given":"Hyung Joon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Urology Konyang University College of Medicine  Daejeon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Seong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Jin","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Urology Chosun University Hospital, Chosun University School of Medicine  Gwangju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyo Serk","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Cheil General Hospital &amp; Women's Healthcare Center, Kwandong University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ha Na","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Ewha Womans University Medical Center, Seoul Seonam Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Wook","family":"You","sequence":"additional","affiliation":[{"name":"Department of Urology Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wonho","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Urology Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyu\u2010Sung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22202"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.4111\/kju.2010.51.1.45"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.5213\/inj.2010.14.4.256"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365599.2012.669789"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199805000-00018"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-008-0560-8"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-010-1162-9"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1224651"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.5213\/inj.2012.16.1.41"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.05.028"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(99)80333-1"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000116772.74358.39"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.08.013"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)69094-3"},{"key":"e_1_2_7_16_1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0094-0143(21)00604-2","article-title":"Surgical management of interstitial cystitis","volume":"21","author":"Irwin PP","year":"1994","journal-title":"Urol. 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