{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:03:34Z","timestamp":1791241414176,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2014,5,7]],"date-time":"2014-05-07T00:00:00Z","timestamp":1399420800000},"content-version":"vor","delay-in-days":36,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract:\u2003<\/jats:title><jats:p>The contents and understanding of the term, interstitial cystitis, have undergone major changes during the past 100 years, moving from a chronic, true inflammatory bladder disorder to an extensive syndrome with lower urinary tract pain. Comments on this development are presented. From examples in the literature, some important features of classic interstitial cystitis are outlined. The more inclusive attitude of later decades has drawn desirable attention to the entire spectrum of disorders resulting in bladder pain. The wish to include all of them into one handy entity has unfortunately resulted in much scientific and clinical confusion, though. It is noted that originally interstitial cystitis represented the <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>unner type of disease. Today, there is agreement that the classic type of interstitial cystitis with <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>unner's lesions, bladder pain syndrome type <jats:styled-content style=\"fixed-case\">3C<\/jats:styled-content> according to current terminology, stands out as a well\u2010defined phenotype; it has to evaluated separately in clinical studies and practice, as treatment requirements differ importantly between this and other phenotypes<\/jats:p>","DOI":"10.1111\/iju.12325","type":"journal-article","created":{"date-parts":[[2014,5,8]],"date-time":"2014-05-08T02:46:29Z","timestamp":1399517189000},"page":"79-82","source":"Crossref","is-referenced-by-count":50,"title":["Interstitial cystitis is bladder pain syndrome with <scp>H<\/scp>unner's lesion"],"prefix":"10.1111","volume":"21","author":[{"given":"Magnus","family":"Fall","sequence":"first","affiliation":[{"name":"Department of Urology Sahlgrenska Academy at Gothenburg University and Sahlgrenska University Hospital  G\u00f6teborg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yr","family":"Logadottir","sequence":"additional","affiliation":[{"name":"Department of Urology Sahlgrenska Academy at Gothenburg University and Sahlgrenska University Hospital  G\u00f6teborg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"Peeker","sequence":"additional","affiliation":[{"name":"Department of Urology Sahlgrenska Academy at Gothenburg University and Sahlgrenska University Hospital  G\u00f6teborg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,7]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Diseases of Bladder and Urethra in Women","author":"Skene AJC","year":"1887"},{"key":"e_1_2_6_3_1","first-page":"374","article-title":"Elusive ulcer of the bladder: further notes on a rare type of bladder ulcer with report of 25 cases","volume":"78","author":"Hunner GL","year":"1918","journal-title":"Am. J. Obstet."},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)69067-0"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(78)90286-8"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)43863-8"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65006-9"},{"key":"e_1_2_6_8_1","first-page":"13","volume-title":"Intersititial Cystitis","author":"Wein A","year":"1990"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2003.11.021"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.09.019"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2005.08.054"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12165"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)62376-0"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08847.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2008.02179.x"},{"key":"e_1_2_6_16_1","first-page":"411","article-title":"Proliferation and transepithelial migration of mucosal mast cells in interstitial cystitis","volume":"58","author":"Aldenborg F","year":"1986","journal-title":"Immunology"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)49221-4"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67873-1"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)40201-1"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.08.096"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.07576.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)64317-9"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)39611-8"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.03.184"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365599.2012.699100"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1982.tb06976.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2006.08.1109"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2007.00519.x"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.08097.x"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000110501.96416.40"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.09.142"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-010-1129-x"}],"container-title":["International Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fiju.12325","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iju.12325","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T16:58:41Z","timestamp":1694451521000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iju.12325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":31,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1111\/iju.12325"],"URL":"https:\/\/doi.org\/10.1111\/iju.12325","archive":["Portico"],"relation":{},"ISSN":["0919-8172","1442-2042"],"issn-type":[{"value":"0919-8172","type":"print"},{"value":"1442-2042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4]]}}}