{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:39:10Z","timestamp":1790199550087,"version":"4.1.0"},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,11,19]],"date-time":"2013-11-19T00:00:00Z","timestamp":1384819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract:\u2003<\/jats:title><jats:p>The present case report describes two cases of unresectable advanced primary urethral carcinoma. Case 1 was a 61\u2010year\u2010old man with squamous cell carcinoma of the urethra that directly invaded into the perineal skin. Case 2 was a 64\u2010year\u2010old woman with adenocarcinoma, and solitary lung and lymph node metastases. Both patients received docetaxel\/cisplatin\/5\u2010fluorouracil chemotherapy with concurrent radiation. The docetaxel\/cisplatin\/5\u2010fluorouracil chemotherapy regimen consisted of docetaxel (75\u2009mg\/m<jats:sup>2<\/jats:sup>) on day 2, cisplatin (100\u2009mg\/m<jats:sup>2<\/jats:sup>) on day 2 and 5\u2010fluorouracil (1000\u2009mg\/m<jats:sup>2<\/jats:sup>) on days 1 to 5 and was repeated every 4 weeks. Complete response was achieved after two cycles of chemotherapy combined with radiation in case 1. In case 2, complete response was achieved locally after six cycles of chemotherapy combined with radiation, but the solitary lung lesion remained viable. We experienced two cases with advanced urethral carcinoma for whom docetaxel\/cisplatin\/5\u2010fluorouracil chemotherapy chemotherapy with radiation was effective.<\/jats:p>","DOI":"10.1111\/iju.12333","type":"journal-article","created":{"date-parts":[[2013,11,19]],"date-time":"2013-11-19T23:48:56Z","timestamp":1384904936000},"page":"422-424","source":"Crossref","is-referenced-by-count":11,"title":["Docetaxel, cisplatin and 5\u2010fluorouracil chemotherapy with concurrent radiation for unresectable advanced urethral carcinoma"],"prefix":"10.1111","volume":"21","author":[{"given":"Jun","family":"Itoh","sequence":"first","affiliation":[{"name":"Department of Urology Tohoku University School of Medicine  Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Mitsuzuka","sequence":"additional","affiliation":[{"name":"Department of Urology Tohoku University School of Medicine  Sendai 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