{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:35:41Z","timestamp":1790008541612,"version":"4.0.1"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,4,13]],"date-time":"2014-04-13T00:00:00Z","timestamp":1397347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the impact of renal graft nephrectomy on second kidney transplantation survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We carried out a retrospective single\u2010center study by analyzing cases performed from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2000 to <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2011. Retransplanted patients who underwent previous allograft nephrectomy more than 3\u2009months post\u2010transplantation (group\u20091) were compared with those who did not (group\u20092) in terms of graft survival, incidences of acute rejection and delayed graft function. Multivariate <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ox proportional hazard models were used to assess risk factors of graft loss after retransplantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 146 patients were analyzed, including 52 (35.6%) in group\u20091 and 94 (64.4%) in group\u20092. Group\u20091 patients presented a significantly shorter first graft survival (0.8 <jats:italic>vs<\/jats:italic> 8.6\u2009years, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and more anti\u2010class\u2009<jats:styled-content style=\"fixed-case\">I<\/jats:styled-content> antibodies (90.5% <jats:italic>vs<\/jats:italic> 74.2%, <jats:italic>P<\/jats:italic>\u2009=\u20090.03). A total of 10 patients (19%) in group\u20091 and 16 patients (17%) in group\u20092 had at least one acute rejection episode (<jats:italic>P<\/jats:italic>\u2009=\u20090.74). Delayed graft function was observed in 13 patients (25%) in group\u20091 and 17 patients (18%) in group\u20092 (<jats:italic>P<\/jats:italic>\u2009=\u20090.32). Graft survival at 1, 5 and 10\u2009years was, respectively, 94%, 81% and 58% in group\u20091, and 99%, 93% and 66% in group\u20092 (<jats:italic>P<\/jats:italic>\u2009=\u20090.10). Graft survival was decreased by increased donor age and serum creatinine, and tended to be associated with post\u2010transplantation presence of anti\u2010class\u2009<jats:styled-content style=\"fixed-case\">I<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> antibodies. Graft nephrectomy was not associated with graft survival in multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Graft nephrectomy, probably a marker of high immunological risk patients, is not a risk factor of increased retransplant failure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.12455","type":"journal-article","created":{"date-parts":[[2014,4,14]],"date-time":"2014-04-14T00:14:55Z","timestamp":1397434495000},"page":"797-802","source":"Crossref","is-referenced-by-count":26,"title":["Impact of graft nephrectomy on outcomes of second kidney transplantation"],"prefix":"10.1111","volume":"21","author":[{"given":"Sa\u00e2d Ed\u2010Dine","family":"Fadli","sequence":"first","affiliation":[{"name":"Department of Urology and Transplantation University Hospital of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Pernin","sequence":"additional","affiliation":[{"name":"Department of Nephrology University Hospital of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Nogue","sequence":"additional","affiliation":[{"name":"Unit of Clinical Research and Epidemiology Department of Medical Information CHU Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Macioce","sequence":"additional","affiliation":[{"name":"Unit of Clinical Research and Epidemiology Department of Medical Information CHU Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Christine","family":"Picot","sequence":"additional","affiliation":[{"name":"Unit of Clinical Research and Epidemiology Department of Medical Information CHU Montpellier  Montpellier France"},{"name":"Clinical Investigation Center  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie","family":"Ramounau\u2010Pigot","sequence":"additional","affiliation":[{"name":"Department of Immunology University Hospital of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Garrigue","sequence":"additional","affiliation":[{"name":"Department of Nephrology University Hospital of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Iborra","sequence":"additional","affiliation":[{"name":"Department of Urology and Transplantation University Hospital of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georges","family":"Mourad","sequence":"additional","affiliation":[{"name":"Department of Nephrology University Hospital of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolphe","family":"Thuret","sequence":"additional","affiliation":[{"name":"Department of Urology and Transplantation University Hospital of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V123589"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199812270-00014"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000235434.13327.11"},{"key":"e_1_2_8_5_1","unstructured":"Agence de biom\u00e9decine Medical and scientific report. rapport_rein2011. 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