{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T13:21:47Z","timestamp":1790601707271,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,6,10]],"date-time":"2014-06-10T00:00:00Z","timestamp":1402358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the surgical outcomes of laparoscopic radical prostatectomy and robot\u2010assisted radical prostatectomy, including the frequency and location of positive surgical margins.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study cohort comprised 708 consecutive male patients with clinically localized prostate cancer who underwent laparoscopic radical prostatectomy (<jats:italic>n<\/jats:italic>\u2009=\u2009551) or robot\u2010assisted radical prostatectomy (<jats:italic>n<\/jats:italic>\u2009=\u2009157) between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 1999 and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eptember 2012. Operative time, estimated blood loss, complications, and positive surgical margins frequency were compared between laparoscopic radical prostatectomy and robot\u2010assisted radical prostatectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no significant differences in age or body mass index between the laparoscopic radical prostatectomy and robot\u2010assisted radical prostatectomy patients. Prostate\u2010specific antigen levels, <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>leason sum and clinical stage of the robot\u2010assisted radical prostatectomy patients were significantly higher than those of the laparoscopic radical prostatectomy patients. Robot\u2010assisted radical prostatectomy patients suffered significantly less bleeding (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The overall frequency of positive surgical margins was 30.6% (<jats:italic>n<\/jats:italic>\u2009=\u2009167; 225 sites) in the laparoscopic radical prostatectomy group and 27.5% (<jats:italic>n<\/jats:italic>\u2009=\u200942; 58 sites) in the robot\u2010assisted radical prostatectomy group. In the laparoscopic radical prostatectomy group, positive surgical margins were detected in the apex (52.0%), anterior (5.3%), posterior (5.3%) and lateral regions (22.7%) of the prostate, as well as in the bladder neck (14.7%). In the robot\u2010assisted radical prostatectomy patients, they were observed in the apex, anterior, posterior, and lateral regions of the prostate in 43.0%, 6.9%, 25.9% and 15.5% of patients, respectively, as well as in the bladder neck in 8.6% of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Positive surgical margin distributions after robot\u2010assisted radical prostatectomy and laparoscopic radical prostatectomy are significantly different. The only disadvantage of robot\u2010assisted radical prostatectomy is the lack of tactile feedback. Thus, the robotic surgeon needs to take this into account to minimize the risk of positive surgical margins.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.12492","type":"journal-article","created":{"date-parts":[[2014,6,10]],"date-time":"2014-06-10T09:47:31Z","timestamp":1402393651000},"page":"976-979","source":"Crossref","is-referenced-by-count":14,"title":["Pitfalls of robot\u2010assisted radical prostatectomy: A comparison of positive surgical margins between robotic and laparoscopic surgery"],"prefix":"10.1111","volume":"21","author":[{"given":"Keiichi","family":"Tozawa","sequence":"first","affiliation":[{"name":"Department of Nephro\u2010urology Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Yasui","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiro","family":"Umemoto","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriyasu","family":"Kawai","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Experimental Pathology and Tumor Biology Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenjiro","family":"Kohri","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,6,10]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"11","article-title":"Outcomes of robot\u2010assisted laparoscopic prostatectomy with a posterior approach to the seminal vesicle in 150 Japanese patients","volume":"53","author":"Yasui T","year":"2013","journal-title":"Nagoya Med. 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