{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T15:51:01Z","timestamp":1789573861490,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,7,30]],"date-time":"2014-07-30T00:00:00Z","timestamp":1406678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To validate two prediction models (<jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>rganization for <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>esearch and <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ancer and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>panish <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>rological <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>lub for <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ncological <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment) for recurrence and progression of non\u2010muscle invasive bladder cancer in <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apanese patients who underwent bacillus <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>almette\u2013<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>u\u00e9rin instillation therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 1985 to <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pril 2007, data were analyzed from 366 patients who underwent transurethral resection of bladder tumor followed by bacillus <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>almette\u2013<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>u\u00e9rin instillation therapy. The ability of two scoring models to predict recurrence and progression was assessed by concordance index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For recurrence probability, the concordance index of the <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>rganization for <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>esearch and <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ancer and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>panish <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>rological <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>lub for <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ncological <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment models was 0.514 and 0.576, respectively, which was lower than that (0.604) of a selected single prognostic factor (age) by our multivariate analysis. For progression probability, the concordance index of <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>rganization for <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>esearch and <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ancer and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>panish <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>rological <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>lub for <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ncological <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment models was 0.693 and 0.764, respectively, which was higher than that (0.633) of a selected single factor (<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content> stage) by our multivariate analysis. The <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>panish <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>rological <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>lub for <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ncological <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment scoring system resulted in better stratification of tumor recurrence and progression when compared with the <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>rganization for <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>esearch and <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ancer model, probably because more patients underwent bacillus <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>almette\u2013<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>u\u00e9rin treatment in the <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>panish <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>rological <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>lub for <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ncological <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment cohort than in the <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>rganization for <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>esearch and <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ancer cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>panish <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>rological <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>lub for <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ncological <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>reatment scoring system is a good predictor of tumor recurrence and progression in <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apanese patients who underwent bacillus <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>almette\u2013<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>u\u00e9rin immunotherapy. A large prospective study is warranted to confirm the efficacy of this system.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.12572","type":"journal-article","created":{"date-parts":[[2014,7,30]],"date-time":"2014-07-30T05:57:20Z","timestamp":1406699840000},"page":"1201-1207","source":"Crossref","is-referenced-by-count":19,"title":["External validation of <scp>E<\/scp>uropean <scp>O<\/scp>rganization for <scp>R<\/scp>esearch and <scp>T<\/scp>reatment of <scp>C<\/scp>ancer and <scp>S<\/scp>panish <scp>U<\/scp>rological <scp>C<\/scp>lub for <scp>O<\/scp>ncological <scp>T<\/scp>reatment scoring models to predict recurrence and progression in <scp>J<\/scp>apanese patients with non\u2010muscle invasive bladder cancer treated with bacillus <scp>C<\/scp>almette\u2013<scp>G<\/scp>u\u00e9rin"],"prefix":"10.1111","volume":"21","author":[{"given":"Yasuo","family":"Kohjimoto","sequence":"first","affiliation":[{"name":"Department of Urology Wakayama Medical University  Wakayama 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