{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T02:27:31Z","timestamp":1773023251025,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,3,5]],"date-time":"2015-03-05T00:00:00Z","timestamp":1425513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To further elucidate the mechanisms of overactive bladder coexisting with pelvic organ prolapse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 100 consecutive women with stage\u20092 or greater pelvic organ prolapse associated with cystocele were enrolled in the present prospective study. They underwent urodynamic studies and then received tension\u2010free vaginal mesh operation. Urodynamic studies were carried out before and after the correction of pelvic organ prolapse using a single gauze pack in the vagina in the sitting position. The overactive bladder symptom score and International Prostate Symptom Score were collected before and 3\u2009months after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 53 of 100 cases, pelvic organ prolapse was accompanied with overactive bladder, and detrusor overactivity was observed in 28 out of 53 pelvic organ prolapse with overactive bladder cases (52.8%). Detrusor overactivity was resolved in 18 and reduced in four out of 28 cases after the correction of pelvic organ prolapse by the gauze packing method. Of 53 patients who had overactive bladder preoperatively, overactive bladder symptoms disappeared in 35 cases (66.0%) and improved in six additional cases (11.3%) after tension\u2010free vaginal mesh operation. A total of 20 of 25 cases whose overactive bladder symptoms disappeared or improved after surgery coincided with those who had shown either disappearance (<jats:italic>n<\/jats:italic>\u2009=\u200916) or improvement (<jats:italic>n<\/jats:italic>\u2009=\u20094) of detrusor overactivity after intravaginal gauze pack insertion in preoperative urodynamic studies. All scores in the overactive bladder symptom score decreased significantly after tension\u2010free vaginal mesh, as well as the International Prostate Symptom Score, except for night\u2010time frequency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pelvic organ prolapse\u2010associated overactive bladder or detrusor overactivity conditions can be reversed in most cases within a short period of time after surgical correction of pelvic organ prolapse.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.12744","type":"journal-article","created":{"date-parts":[[2015,3,6]],"date-time":"2015-03-06T01:08:57Z","timestamp":1425604137000},"page":"577-580","source":"Crossref","is-referenced-by-count":16,"title":["Improvement of overactive bladder symptoms after tension\u2010free vaginal mesh operation in women with pelvic organ prolapse: Correlation with preoperative urodynamic findings"],"prefix":"10.1111","volume":"22","author":[{"given":"Hikaru","family":"Tomoe","sequence":"first","affiliation":[{"name":"Department of Pelvic Reconstructive Surgery, Urology Tokyo Women's Medical University Medical Center East  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00568.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181660c1b"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0368-2315(04)96598-2"},{"issue":"1","key":"e_1_2_8_5_1","first-page":"S46","article-title":"Feasibility of the tension\u2010free vaginal mesh procedure using soft polypropylene mesh (Gynemesh PS) Japan","volume":"18","author":"Takeyama M","year":"2007","journal-title":"Int. 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