{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T17:24:27Z","timestamp":1784827467762,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,8,30]],"date-time":"2015-08-30T00:00:00Z","timestamp":1440892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To analyze long\u2010term changes in both kidneys, and to predict renal function and contralateral hypertrophy after robot\u2010assisted partial nephrectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 62 patients underwent robot\u2010assisted partial nephrectomy, and renal parenchymal volume was calculated using three\u2010dimensional semi\u2010automatic segmentation technology. Patients were evaluated within 1\u00a0month preoperatively, and postoperatively at 6\u00a0months, 1\u00a0year and continued up to 2\u2010year follow up. Linear regression models were used to identify the factors predicting variables that correlated with estimated glomerular filtration rate changes and contralateral hypertrophy 2\u00a0years after robot\u2010assisted partial nephrectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median global estimated glomerular filtration rate changes were \u221210.4%, \u221211.9%, and \u22122.4% at 6\u00a0months, 1 and 2\u00a0years post\u2010robot\u2010assisted partial nephrectomy, respectively. The ipsilateral kidney median parenchymal volume changes were \u221224%, \u221224.4%, and \u221221% at 6\u00a0months, 1 and 2\u00a0years post\u2010robot\u2010assisted partial nephrectomy, respectively. The contralateral renal volume changes were 2.3%, 9.6% and 12.9%, respectively. On multivariable linear analysis, preoperative estimated glomerular filtration rate was the best predictive factor for global estimated glomerular filtration rate change on 2\u00a0years post\u2010robot\u2010assisted partial nephrectomy (<jats:italic>B<\/jats:italic> \u22120.452; 95% confidence interval \u22120.84 to \u22120.14; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.021), whereas the parenchymal volume loss rate (<jats:italic>B<\/jats:italic> \u22120.43; 95% confidence interval \u22120.89 to \u22120.15; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.017) and tumor size (<jats:italic>B<\/jats:italic> 5.154; 95% confidence interval \u22120.11 to 9.98; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.041) were the significant predictive factors for the degree of contralateral renal hypertrophy on 2\u00a0years post\u2010robot\u2010assisted partial nephrectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Preoperative estimated glomerular filtration rate significantly affects post\u2010robot\u2010assisted partial nephrectomy renal function. Renal mass size and renal parenchyma volume loss correlates with compensatory hypertrophy of the contralateral kidney. Contralateral hypertrophy of the renal parenchyma compensates for the functional loss of the ipsilateral kidney.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.12913","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T14:54:50Z","timestamp":1441205690000},"page":"1105-1111","source":"Crossref","is-referenced-by-count":13,"title":["Two\u2010year analysis for predicting renal function and contralateral hypertrophy after robot\u2010assisted partial nephrectomy: A three\u2010dimensional segmentation technology study"],"prefix":"10.1111","volume":"22","author":[{"given":"Dae Keun","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Urology Urological Science Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujin","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Multimedia Engineering Seoul Women's University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaeseon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Multimedia Engineering Seoul Women's University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Multimedia Engineering Seoul Women's University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Hong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology Urological Science Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Young","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Urology Chuncheon Sacred Hospital Hallym University College of Medicine Chuncheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae Chul","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiological Science Yonsei University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Deuk","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Urology Urological Science Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koon Ho","family":"Rha","sequence":"additional","affiliation":[{"name":"Department of Urology Urological Science Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,8,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clgc.2014.07.011"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.12.030"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.12.068"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.11.071"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.06.046"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2013.10.058"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-130-6-199903160-00002"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08376.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.04.016"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.05.008"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.05.047"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12766"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.11.037"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2013.03.068"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.09.131"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.07.084"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00442612"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2011.02864.x"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.06.018"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1998.00871.x"},{"key":"e_1_2_8_22_1","first-page":"1413","article-title":"Role of nitric oxide in the renal hemodynamic response to unilateral nephrectomy","volume":"15","author":"Sigmon DH","year":"2004","journal-title":"Int. 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