{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T08:44:05Z","timestamp":1696409045904},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T00:00:00Z","timestamp":1450656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The management of acute scrotum can be challenging, especially in infants or patients with a neurological or neurodevelopmental disorder in whom presentation, diagnosis and definitive management tends to be delayed. This leads to poor outcomes, such as loss of the affected testis. Here we present two cases of testicular torsion in patients with neurodevelopmental disorders, and a further two cases of epidydimo\u2010orchitis in whom measurement of CD64 expression on neutrophils was helpful for differential diagnosis. These data suggest that the levels of expression of CD64 by neutrophils, known as a marker of infection, could also be useful for differentiating between testicular torsion and infection in acute scrotum.<\/jats:p>","DOI":"10.1111\/iju.13036","type":"journal-article","created":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T23:54:44Z","timestamp":1450742084000},"page":"266-269","source":"Crossref","is-referenced-by-count":0,"title":["Clinical application of neutrophil CD64 quantification for differential diagnosis of acute scrotum"],"prefix":"10.1111","volume":"23","author":[{"given":"Hirofumi","family":"Hayashi","sequence":"first","affiliation":[{"name":"Department of Urology National Hospital Organization Sagamihara National Hospital Sagamihara, Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taku","family":"Mochizuki","sequence":"additional","affiliation":[{"name":"Department of Urology National Hospital Organization Sagamihara National Hospital Sagamihara, Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Sanjo","sequence":"additional","affiliation":[{"name":"Department of Urology National Hospital Organization Sagamihara National Hospital Sagamihara, Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Komiya","sequence":"additional","affiliation":[{"name":"Department of Rheumatology National Hospital Organization Sagamihara National Hospital Sagamihara, Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Matsui","sequence":"additional","affiliation":[{"name":"Department of Rheumatology National Hospital Organization Sagamihara National Hospital Sagamihara, Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeto","family":"Tohma","sequence":"additional","affiliation":[{"name":"Department of Rheumatology National Hospital Organization Sagamihara National Hospital Sagamihara, Kanagawa Japan"},{"name":"Department of Clinical Laboratory National Hospital Organization Sagamihara National Hospital Sagamihara, Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kotaro","family":"Hirai","sequence":"additional","affiliation":[{"name":"Department of Urology National Hospital Organization Sagamihara National Hospital Sagamihara, Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2007.05.008"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/145749691110000311"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00031-13"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12470"},{"key":"e_1_2_6_6_1","first-page":"2416","article-title":"CD64 on neutrophils is a sensitive and specific marker for detection of infection in patients with rheumatoid arthritis","volume":"33","author":"Matsui T","year":"2006","journal-title":"J. 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