{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:08:07Z","timestamp":1762542487039,"version":"3.37.3"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T00:00:00Z","timestamp":1453248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005992","name":"Ministry of Education, Science and Culture","doi-asserted-by":"crossref","award":["23592385"],"award-info":[{"award-number":["23592385"]}],"id":[{"id":"10.13039\/501100005992","id-type":"DOI","asserted-by":"crossref"}]},{"name":"MEXT-Supported Program for the Strategic Research Foundation at Private Universities","award":["S1001035"],"award-info":[{"award-number":["S1001035"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Kidneys procured from the deceased hold great potential for expanding the donor pool. The aims of the present study were to investigate the post\u2010transplant outcomes of renal allografts recovered from donors after cardiac death, to identify risk factors affecting the renal prognosis and to compare the long\u2010term survival from donors after cardiac death according to the number of risk factors shown by expanded criteria donors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 443 grafts recovered using an <jats:italic>in situ<\/jats:italic> regional cooling technique from 1983 to 2011 were assessed. To assess the combined predictive value of the significant expanded criteria donor risk criteria, the patients were divided into three groups: those with no expanded criteria donor risk factors (no risk), one expanded criteria donor risk factor (single\u2010risk) and two or more expanded criteria donor risk factors (multiple\u2010risk).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the donor factors, age \u226550 years, hypertension, maximum serum creatinine level \u22651.5 mg\/dL and a warm ischemia time \u226530 min were identified as independent predictors of long\u2010term graft failure on multivariate analysis. Regarding the expanded criteria donors criteria for marginal donors, cerebrovascular disease, hypertension and maximum serum creatinine level \u22651.5 mg\/dL were identified as significant predictors on univariate analysis. The single\u2010 and multiple\u2010risk groups showed 2.01\u2010 and 2.40\u2010fold higher risks of graft loss, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Renal grafts recovered from donors after cardiac death donors have a good renal function with an excellent long\u2010term graft survival. However, an increased number of expanded criteria donors risk factors increase the risk of graft loss.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.13045","type":"journal-article","created":{"date-parts":[[2016,1,21]],"date-time":"2016-01-21T02:31:36Z","timestamp":1453343496000},"page":"319-324","source":"Crossref","is-referenced-by-count":9,"title":["Combined predictive value of the expanded donor criteria for long\u2010term graft survival of kidneys from donors after cardiac death: A single\u2010center experience over three decades"],"prefix":"10.1111","volume":"23","author":[{"given":"Mamoru","family":"Kusaka","sequence":"first","affiliation":[{"name":"Department of Urology Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Kubota","sequence":"additional","affiliation":[{"name":"Department of Urology Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitomi","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Urology Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naohiko","family":"Fukami","sequence":"additional","affiliation":[{"name":"Department of Urology Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamio","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of Urology Nagoya Memorial Hospital Nagoya Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Hirose","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Division of Medical Statistics Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Kenmochi","sequence":"additional","affiliation":[{"name":"Department of Organ Transplant Surgery Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryoichi","family":"Shiroki","sequence":"additional","affiliation":[{"name":"Department of Urology Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyotaka","family":"Hoshinaga","sequence":"additional","affiliation":[{"name":"Department of Urology Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)90815-3"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3727\/000000008783907116"},{"key":"e_1_2_8_4_1","first-page":"213","article-title":"The fate of 359 renal allografts harvested from non\u2010heart beating cadaver donors at a single center","author":"Hoshinaga K","year":"1998","journal-title":"Clin. 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