{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:41:13Z","timestamp":1788864073454,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the diagnostic performance of computed tomography, magnetic resonance imaging and contrast enhanced ultrasonography for the assessment of complex renal cysts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We carried out a prospective single\u2010center study from January 2012 to December 2013. We included patients with Bosniak category 2F or 3 renal cysts found on <jats:styled-content style=\"fixed-case\">computed tomography<\/jats:styled-content> and reviewed by two expert radiologists. <jats:styled-content style=\"fixed-case\">Magnetic resonance imaging<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">contrast\u2010enhanced ultrasonography<\/jats:styled-content> were then carried out. Patients with a Bosniak \u22653 cyst on <jats:styled-content style=\"fixed-case\">magnetic resonance imaging,<\/jats:styled-content> as well as those upgraded as appearing malignant on <jats:styled-content style=\"fixed-case\">contrast\u2010enhanced ultrasonography,<\/jats:styled-content> were surgically managed. Imaging results were compared with histological data. For patients without surgery, imaging examinations were compared with follow\u2010up data. For each imaging examination, diagnostic performance and Cohen's kappa coefficient were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 47 patients were included. The median follow up was 36 months (range 17\u201348 months). At initial <jats:styled-content style=\"fixed-case\">computed tomography<\/jats:styled-content>, cysts were classified as Bosniak 2F and Bosniak \u22653 in 34 and 13 patients, respectively. <jats:styled-content style=\"fixed-case\">Magnetic resonance imaging<\/jats:styled-content> found 13 Bosniak \u22653 cysts, and <jats:styled-content style=\"fixed-case\">contrast\u2010enhanced ultrasonography<\/jats:styled-content> upgraded six more patients with cysts that appeared malignant. A total of 19 patients had surgery. Histological analysis reported 14 malignant tumors. No tumor progression was found in followed\u2010up patients. <jats:styled-content style=\"fixed-case\">Computed tomography<\/jats:styled-content> showed poor sensitivity (36%) and specificity (76%; \u03ba = 0.11). <jats:styled-content style=\"fixed-case\">Magnetic resonance imaging<\/jats:styled-content> showed 71% sensitivity and 91% specificity (\u03ba = 0.64). <jats:styled-content style=\"fixed-case\">Contrast\u2010enhanced ultrasonography<\/jats:styled-content> showed high sensitivity (100%) and specificity (97%), and a negative predictive value at 100% (\u03ba = 0.95).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present results suggested that <jats:styled-content style=\"fixed-case\">contrast\u2010enhanced ultrasonography<\/jats:styled-content> could be useful in improving the assessment of complex renal cysts. Indeed, <jats:styled-content style=\"fixed-case\">computed tomography<\/jats:styled-content> accuracy might be limited in this indication requiring further investigations to determine the best treatment strategy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.13289","type":"journal-article","created":{"date-parts":[[2017,2,2]],"date-time":"2017-02-02T00:48:37Z","timestamp":1485996517000},"page":"184-189","source":"Crossref","is-referenced-by-count":60,"title":["Diagnostic performance of contrast\u2010enhanced ultrasonography and magnetic resonance imaging for the assessment of complex renal cysts: A prospective study"],"prefix":"10.1111","volume":"24","author":[{"given":"Guillaume","family":"Defortescu","sequence":"first","affiliation":[{"name":"Urology Department Rouen University Hospital Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Nicolas","family":"Cornu","sequence":"additional","affiliation":[{"name":"Urology Department Rouen University 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