{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T04:07:07Z","timestamp":1744603627762},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,1,25]],"date-time":"2017-01-25T00:00:00Z","timestamp":1485302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Pressure flow studies are regarded as the gold standard for evaluating both bladder outlet obstruction and detrusor contractility, but none of the current methods for evaluating bladder contraction patterns are well validated. Impaired bladder contraction results in a lower peak Watts factor and poorly sustained detrusor contractions. From this viewpoint, the maximum <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content> and its pattern should be considered separately. To examine detrusor contraction pattern in patients after radical prostatectomy by using multiple parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 37 patients with clinically localized prostate cancer underwent both pre\u2010 and post\u2010radical prostatectomy urodynamic evaluations. The examined urodynamic parameters included the maximum flow rate, post\u2010void residual volume, detrusor pressure at maximum flow, maximum <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">relative volume <\/jats:styled-content>(maximum <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content>). Some parameters were defined from the Watts factor curve throughout micturition. <jats:styled-content style=\"fixed-case\">Relative volume <\/jats:styled-content>(maximum <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content>) was the relative bladder volume at the maximum <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content>. A normal detrusor contractility pattern involves an increase in <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content> at the initiation followed by further gradual increases until the end of micturition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Maximum flow rate increased significantly after <jats:styled-content style=\"fixed-case\">radical prostatectomy<\/jats:styled-content> (pre: 13.0\u00a0\u00b1\u00a06.5, post: 17.3\u00a0\u00b1\u00a07.7\u00a0mL\/min; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01), whereas detrusor pressure at maximum flow and <jats:styled-content style=\"fixed-case\">post\u2010void residual volume<\/jats:styled-content> decreased significantly (pre: 49.6\u00a0\u00b1\u00a021.6 and 31.4\u00a0\u00b1\u00a018.2\u00a0cmH<jats:sub>2<\/jats:sub>O; post: 48.6\u00a0\u00b1\u00a066.1 and 10.1\u00a0\u00b1\u00a028.5\u00a0mL; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). Maximum <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content> did not change significantly after <jats:styled-content style=\"fixed-case\">radical prostatectomy<\/jats:styled-content> (pre: 10.5\u00a0\u00b1\u00a03.1\u00a0W\/m<jats:sup>2<\/jats:sup>, post: 11.0\u00a0\u00b1\u00a03.2\u00a0W\/m<jats:sup>2<\/jats:sup>), but <jats:styled-content style=\"fixed-case\">relative volume <\/jats:styled-content>(maximum <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content>) decreased significantly (pre: 0.48\u00a0\u00b1\u00a00.3, post: 0.20\u00a0\u00b1\u00a00.20; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Maximum <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content> represents the maximum power of bladder contraction at a particular point in time, whereas <jats:styled-content style=\"fixed-case\">relative volume <\/jats:styled-content>(maximum <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content>) can be used to detect changes in detrusor contraction pattern.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Evaluation of <jats:styled-content style=\"fixed-case\">relative volume <\/jats:styled-content>(maximum <jats:styled-content style=\"fixed-case\">Watts factor<\/jats:styled-content>) confirms that <jats:styled-content style=\"fixed-case\">radical prostatectomy<\/jats:styled-content> restores the normal detrusor contractility pattern in prostate cancer patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.13295","type":"journal-article","created":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T00:08:39Z","timestamp":1485389319000},"page":"301-307","source":"Crossref","is-referenced-by-count":7,"title":["Radical prostatectomy restores detrusor contraction pattern according to pressure flow parameters"],"prefix":"10.1111","volume":"24","author":[{"given":"Takeya","family":"Kitta","sequence":"first","affiliation":[{"name":"Department of Renal and Genitourinary Surgery Graduate School of Medicine, Hokkaido University Sapporo Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiko","family":"Kanno","sequence":"additional","affiliation":[{"name":"Department of Renal and Genitourinary Surgery Graduate School of Medicine, Hokkaido University Sapporo Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Chiba","sequence":"additional","affiliation":[{"name":"Department of Renal and Genitourinary Surgery Graduate School of Medicine, Hokkaido University Sapporo Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimihiko","family":"Moriya","sequence":"additional","affiliation":[{"name":"Department of Renal and Genitourinary Surgery Graduate School of Medicine, Hokkaido University Sapporo Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Renal and Genitourinary Surgery Graduate School of Medicine, Hokkaido University Sapporo Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashige","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Renal and Genitourinary Surgery Graduate School of Medicine, Hokkaido University Sapporo Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Shinohara","sequence":"additional","affiliation":[{"name":"Department of Renal and Genitourinary Surgery Graduate School of Medicine, Hokkaido University Sapporo Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,1,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djq154"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000118957.24390.66"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67538-6"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000059700.21764.83"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.10052"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1757-5672.2011.00133.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6777(1998)17:6<621::AID-NAU6>3.0.CO;2-4"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.10066"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)37049-0"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-0143(05)70318-9"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00182664"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00182666"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.21097"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00571750"},{"key":"e_1_2_8_16_1","first-page":"569","article-title":"Critical review of the uroflowmetry","volume":"5","author":"AbdelMagid ME","year":"1998","journal-title":"Can. 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