{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:17:20Z","timestamp":1770769040369,"version":"3.50.0"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T00:00:00Z","timestamp":1487635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To examine resistant <jats:italic>Escherichia coli<\/jats:italic> in rectal swab culture of Japanese men undergoing prostate biopsy, and to determine its prevalence, genotypic characteristics and carriage risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Rectal swabs of consecutive men undergoing transrectal ultrasound\u2010guided prostate biopsy from April 2013 to March 2015 were cultured to isolate fluoroquinolone\u2010resistant and extended\u2010spectrum \u03b2\u2010lactamase\u2010producing <jats:italic>E. coli<\/jats:italic>. The prevalence and antimicrobial susceptibility of these resistant <jats:italic>E. coli<\/jats:italic> strains and extended\u2010spectrum \u03b2\u2010lactamase genotyping were examined. The risk factors of antimicrobial resistance carriage were also examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The cohort was 376 men with a mean age of 67.8 years. Fluoroquinolone\u2010resistant <jats:italic>E. coli<\/jats:italic> and extended\u2010spectrum \u03b2\u2010lactamase\u2010producing <jats:italic>E. coli<\/jats:italic> were detected in 37 men (9.8%) and 22 men (5.9%), respectively, with fluoroquinolone\u2010resistant and\/or extended\u2010spectrum \u03b2\u2010lactamase\u2010producing <jats:italic>E. coli<\/jats:italic> in 48 men (13.0%). All 49 antimicrobial\u2010resistant strains were susceptible to tazobactam\/piperacillin, amikacin, fosfomycin, meropenem and faropenem. CTX\u2010M\u20109 and CTX\u2010M\u20101 group were detected in 14 (63.6%) and eight (36.4%) men, respectively. CTX\u2010M\u20109 showed relatively higher susceptibility to LVFX and minocycline compared with CTX\u2010M\u20101. Diabetes mellitus was a significant factor for carriage of resistance by multivariate analysis (odds ratio 2.12, <jats:italic>P<\/jats:italic> = 0.039).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present study showed the fecal carriage of fluoroquinolone\u2010resistant <jats:italic>E. coli<\/jats:italic> and extended\u2010spectrum \u03b2\u2010lactamase\u2010producing <jats:italic>E. coli<\/jats:italic> at 9.8% and 5.9%, respectively, with CTX\u2010M\u20109 group of extended\u2010spectrum \u03b2\u2010lactamase\u2010producing <jats:italic>E. coli<\/jats:italic> comprising 63.6%, in Japanese men receiving prostate biopsy. The carriage of fluoroquinolone\u2010resistant and\/or extended\u2010spectrum \u03b2\u2010lactamase\u2010producing <jats:italic>E. coli<\/jats:italic> was significantly related to diabetes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.13308","type":"journal-article","created":{"date-parts":[[2017,2,22]],"date-time":"2017-02-22T00:06:59Z","timestamp":1487722019000},"page":"295-300","source":"Crossref","is-referenced-by-count":15,"title":["Prevalence and characteristics of fecal antimicrobial\u2010resistant <i>Escherichia coli<\/i> in a cohort of Japanese men undergoing prostate biopsy"],"prefix":"10.1111","volume":"24","author":[{"given":"Jun","family":"Kamei","sequence":"first","affiliation":[{"name":"Department of Urology Graduate School of Medicine The University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuka","family":"Yagihara","sequence":"additional","affiliation":[{"name":"Department of Infection Control and Prevention University of Tokyo 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