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The target patients are men aged &gt;50 years complaining of lower urinary tract symptoms, with or without benign prostatic hyperplasia, and the target readers are non\u2010urological general physicians and urologists. Mandatory assessment for general physicians is medical history, physical examination, urinalysis and measurement of serum prostate\u2010specific antigen. Additional mandatory assessment for urologists is symptoms and quality of life assessment by questionnaires, uroflowmetry, residual urine measurement, and prostate ultrasonography. Nocturia requires special attention, as it can result from nocturnal polyuria and\/or sleep disturbance rather than lower urinary tract disorders. Functional\n                    <jats:styled-content style=\"fixed-case\">lower urinary tract disorders<\/jats:styled-content>\n                    with or without\n                    <jats:styled-content style=\"fixed-case\">benign prostatic hyperplasia<\/jats:styled-content>\n                    are primarily managed by conservative therapy and medications, such as \u03b1\n                    <jats:sub>1<\/jats:sub>\n                    \u2010blockers and phosphodiesterase\u2010type 5 inhibitors. Use of other medications or combination pharmacotherapy is to be reserved for urologists. 5\u03b1\u2010Reductase inhibitors and anticholinergics or \u03b23 agonists are indicated for men with enlarged prostates and overactive bladder symptoms, respectively. Surgical intervention for bladder outlet obstruction is considered for persistent symptoms or\n                    <jats:styled-content style=\"fixed-case\">benign prostatic hyperplasia<\/jats:styled-content>\n                    \u2010related comorbidities. Surgical modalities should be optimized by the patient's characteristics, performance of equipment and the surgeon's experience.\n                  <\/jats:p>","DOI":"10.1111\/iju.13401","type":"journal-article","created":{"date-parts":[[2017,7,26]],"date-time":"2017-07-26T20:42:42Z","timestamp":1501101762000},"page":"716-729","source":"Crossref","is-referenced-by-count":121,"title":["Clinical guidelines for male lower urinary tract symptoms and benign prostatic hyperplasia"],"prefix":"10.1111","volume":"24","author":[{"given":"Yukio","family":"Homma","sequence":"first","affiliation":[{"name":"Department of Urology Graduate School of Medicine The University of Tokyo Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Momokazu","family":"Gotoh","sequence":"additional","affiliation":[{"name":"Department of Urology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Kawauchi","sequence":"additional","affiliation":[{"name":"Department of Urology Shiga Medical University Shiga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Kojima","sequence":"additional","affiliation":[{"name":"Department of Urology Fukushima Prefectural University of Medicine Fukushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoya","family":"Masumori","sequence":"additional","affiliation":[{"name":"Department of Urology Sapporo Medical University School of Medicine Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Nagai","sequence":"additional","affiliation":[{"name":"Department of Urology Kawasaki Medical School Kurashiki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadanori","family":"Saitoh","sequence":"additional","affiliation":[{"name":"Department of Urology Sanikukai Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Urology Nagasaki University Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Urology Nihon University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Ukimura","sequence":"additional","affiliation":[{"name":"Department of Urology Kyoto Prefectural University of Medicine Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomonori","family":"Yamanishi","sequence":"additional","affiliation":[{"name":"Department of Urology Dokkyo Medical University Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Department of Urology University of Fukui Fukui Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Urology National Center of Geriatrics and Gerontology Obu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Urology Maeda Clinic of Internal Medicine Ageo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,26]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2009.02369.x"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2011.02860.x"},{"key":"e_1_2_14_4_1","unstructured":"American Urological Association.Management of benign prostatic hyperplasia (BPH) 2010. 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