{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T15:51:13Z","timestamp":1783785073438,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T00:00:00Z","timestamp":1513209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002456","name":"Chonnam National University","doi-asserted-by":"publisher","award":["HCRI 17909\u20101"],"award-info":[{"award-number":["HCRI 17909\u20101"]}],"id":[{"id":"10.13039\/501100002456","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To estimate the prevalence of fluoroquinolone\u2010resistant rectal flora in patients undergoing transrectal ultrasound\u2010guided prostate needle biopsy and to identify the high\u2010risk groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From January 2015 to March 2016, rectal swabs of 557 men who underwent transrectal ultrasound\u2010guided prostate needle biopsy were obtained from five institutions. Clinical variables, including demographics, rectal swab culture results and infectious complications, were evaluated. Univariable and multivariable analyses were used to identify the risk factors for fluoroquinolone resistance of rectal flora and infectious complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence of fluoroquinolone\u2010resistant and extended\u2010spectrum beta\u2010lactamase production was 48.1 and 11.8%, respectively. The most common fluoroquinolone\u2010resistant bacteria was <jats:italic>Escherichia coli<\/jats:italic> (81% of total fluoroquinolone\u2010resistant bacteria, 39% of total rectal flora), and 16 (2.9%) patients had infectious complications. Univariable and multivariable analysis of clinical parameters affecting fluoroquinolone resistance showed no factor associated with fluoroquinolone resistance of rectal flora. The clinical parameter related to infectious complications after prostate biopsy was a history of operation within 6 months (relative risk 6.60; 95% confidence interval 1.99\u201321.8, <jats:italic>P<\/jats:italic> = 0.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings suggest that a risk\u2010based approach by history taking cannot predict antibiotic resistance of rectal flora, and physicians should consider targeted antibiotic prophylaxis or extended antibiotic prophylaxis for Korean patients undergoing transrectal ultrasound\u2010guided prostate biopsy because of high antibiotic resistance of rectal flora.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.13511","type":"journal-article","created":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T23:16:53Z","timestamp":1513293413000},"page":"278-283","source":"Crossref","is-referenced-by-count":26,"title":["Prevalence of fluoroquinolone\u2010resistant rectal flora in patients undergoing transrectal ultrasound\u2010guided prostate needle biopsy: A prospective multicenter study"],"prefix":"10.1111","volume":"25","author":[{"given":"Ho Seok","family":"Chung","sequence":"first","affiliation":[{"name":"Department of Urology Chonnam National University Medical School Gwangju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eu Chang","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Urology Chonnam National University Medical School Gwangju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho Song","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Urology Chonnam National University Medical School Gwangju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Il","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Urology Chonnam National University Medical School Gwangju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun Ju","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Kyung Hee University School of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Hoon","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Urology Chosun University School of Medicine Gwangju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Jin","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Urology Chosun University School of Medicine Gwangju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Sop","family":"Choe","sequence":"additional","affiliation":[{"name":"Department of Urology The Catholic University of Korea St. Vincent's Hospital Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung\u2010Ju","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology The Catholic University of Korea St. Vincent's Hospital Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Woon","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Urology Kwangju Christian Hospital Gwangju 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