{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T10:34:47Z","timestamp":1788345287022,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,6,3]],"date-time":"2018-06-03T00:00:00Z","timestamp":1527984000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To explore the efficacy of psychotherapy combined with drug therapy in patients with category III chronic prostatitis\/chronic pelvic pain syndrome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 156 patients with category III chronic prostatitis\/chronic pelvic pain syndrome were randomly divided into two groups: the control group of 78 patients receiving routine medication; and the intervention group of 78 patients receiving psychological intervention therapy combined with routine medications. Treatment courses were for 3 months. The end\u2010points were the response rate of the National Institutes of Health Chronic Prostatitis Symptom Index, International Index of Erectile Function\u20105, Self\u2010Rating Anxiety Scale, Self\u2010Rating Depression Scale and expressed prostatic secretion\u2010white blood cells.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After 3 months, the average scores of the National Institutes of Health Chronic Prostatitis Symptom Index decreased to 10.1 \u00b1 5.0 in the control group compared with 14.1 \u00b1 4.9 in the intervention group; thus, significant differences were observed between the two groups in the study (<jats:italic>P<\/jats:italic> &lt; 0.001). The average scores of the International Index of Erectile Function\u20105 were improved in the two groups, but compared with the control group, a more marked improvement was detected in the psychological intervention group, and there was a significant difference between the two groups (<jats:italic>P<\/jats:italic> &lt; 0.001). There was significant difference between the two groups in terms of the Self\u2010Rating Anxiety Scale and Self\u2010Rating Depression Scale scores (<jats:italic>P<\/jats:italic> &lt; 0.001). Expressed prostatic secretion\u2010white blood cell counts significantly decreased to 4.4 \u00b1 3.5 in the control group compared with 9.8 \u00b1 3.4 in the intervention group (<jats:italic>P<\/jats:italic> &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Psychological intervention therapy can effectively improve the psychological status and sexual function in patients with category III chronic prostatitis\/chronic pelvic pain syndrome than the routine medication.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.13706","type":"journal-article","created":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T00:03:41Z","timestamp":1528070621000},"page":"710-715","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Psychotherapy combined with drug therapy in patients with category III chronic prostatitis\/chronic pelvic pain syndrome: A randomized controlled trial"],"prefix":"10.1111","volume":"25","author":[{"given":"Jianxin","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Urology Taizhou First People's Hospital Taizhou China"},{"name":"Department of Urology Binzhou Medical University Hospital Binzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuixiang","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Binzhou Medical University Hospital Binzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huijing","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Nursing Binzhou Polytechnical College Binzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianpeng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology Binzhou Central Hospital Binzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongcai","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology Binzhou Medical University Hospital Binzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyuan","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Urology Taizhou First People's Hospital Taizhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,6,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.3.236"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.57.011205.135654"},{"key":"e_1_2_7_4_1","first-page":"723","article-title":"Correlation of the prognosis of chronic prostatitis\/chronic pelvic pain syndrome with psychological and other factors: a Cox regression analysis","volume":"14","author":"Li HC","year":"2008","journal-title":"Zhonghua Znan Ke Xue"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0b013e3283656a55"},{"key":"e_1_2_7_6_1","first-page":"531","article-title":"The severity of psychic symptoms closely correlated with that of clinical ones in chronic prostatitis patients","volume":"13","author":"Zhou Q","year":"2007","journal-title":"Zhonghua Nan Ke Xue"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-013-1083-6"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(01)01151-7"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.06.010"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2015.05.100"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2014.09.012"},{"key":"e_1_2_7_12_1","first-page":"512","article-title":"Investigation and analysis of mental disorders in 1426 cases of chronic prostatitis","volume":"27","author":"Wu LX","year":"2006","journal-title":"Chin. 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