{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T10:57:16Z","timestamp":1779879436766,"version":"3.53.1"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T00:00:00Z","timestamp":1542844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To describe the feasibility of a novel cell\u2010based endoscopic technique using buccal epithelium, expanded and encapsulated in a thermoreversible gelation polymer scaffold for the treatment of urethral stricture.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Six male patients with bulbar urethral stricture ranging from 2.0 to 3.5\u00a0cm in length were included in this pilot study. Autologous buccal epithelial cells from a small buccal mucosal biopsy were isolated, cultured and encapsulated in thermoreversible gelation polymer scaffold, and were implanted at the stricture site after a wide endoscopic urethrotomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All the patients voided well, with a mean peak flow rate of 24\u00a0mL\/s. Urethroscopy carried out at 6\u00a0months showed healthy mucosa at the urethrotomy site. However, two of the six patients had recurrence at 18 and 24\u00a0months, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This endoscopic\u2010based Buccal epithelium Expanded and Encapsulated in Scaffold\u2010Hybrid Approach to Urethral Stricture (BEES\u2010HAUS) technique is a promising alternative for the open substitution buccal graft urethroplasty. It is possible to achieve the benefits of open substitution buccal urethroplasty with this endoscopic technique.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iju.13852","type":"journal-article","created":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T00:59:02Z","timestamp":1542934742000},"page":"253-257","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Buccal epithelium Expanded and Encapsulated in Scaffold\u2010Hybrid Approach to Urethral Stricture (BEES\u2010HAUS) procedure: A novel cell therapy\u2010based pilot study"],"prefix":"10.1111","volume":"26","author":[{"given":"Surya P","family":"Vaddi","sequence":"first","affiliation":[{"name":"Department of Urology and Renal Transplantation Narayana Medical College Hospital Nellore Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijaya B","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation Narayana Medical College Hospital Nellore Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel JK","family":"Abraham","sequence":"additional","affiliation":[{"name":"The Mary\u2010Yoshio Translational Hexagon Nichi\u2010In Center for Regenerative Medicine Chennai Tamil Nadu India"},{"name":"School of Medicine Yamanashi University Yamanashi Japan"},{"name":"Edogawa Evolutionary Laboratory of Science Edogawa Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.03.094"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.01.041"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.06.027"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.85441"},{"key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"e0118653","DOI":"10.1371\/journal.pone.0118653","article-title":"Tissue engineering for human urethral reconstruction: systematic review of recent literature","volume":"10","author":"Kemp V","year":"2015","journal-title":"PLoS ONE"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.15690\/vramn771"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/aja.2012.91"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.01.061"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/10601329409349722"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pat.1994.220050207"},{"key":"e_1_2_8_12_1","first-page":"655","article-title":"Cultivation of human corneal limbal stem cells in Mebiol gel\u2013A thermo\u2010reversible gelation polymer","volume":"124","author":"Sudha B","year":"2006","journal-title":"Indian J. 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