{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T09:38:31Z","timestamp":1766137111628},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T00:00:00Z","timestamp":1543190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008386","name":"Marmara \u00dcniversitesi","doi-asserted-by":"publisher","award":["BSAGC\u2010YLP\u2010040112\u20100002"],"award-info":[{"award-number":["BSAGC\u2010YLP\u2010040112\u20100002"]}],"id":[{"id":"10.13039\/501100008386","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To detect autosomal genetic defects and to determine candidate genes in Sertoli cell\u2010only syndrome infertile men.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Single\u2010nucleotide polymorphism\u00a0+\u00a0comparative genomic hybridization microarray technology was carried out on 39 Sertoli cell\u2010only syndrome infertile patients in the present study. Array comparative genomic hybridization compares the patient's genome against a reference genome, and identifies uncover deletions, amplifications and loss of heterozygosity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A link between defective spermatogenesis genes and infertility was examined, and amplifications and deletions in several genes were detected, including homeobox gene; synaptonemal complex element protein\u00a01; collagen, type\u00a0I, alpha\u00a01; imprinted maternally expressed transcript; and potassium voltage\u2010gated channel subfamily\u00a0Q member\u00a01.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present data suggest that several genes can play an important role in spermatogenesis and progression of Sertoli cell\u2010only syndrome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.13863","type":"journal-article","created":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T02:45:16Z","timestamp":1543286716000},"page":"292-298","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Male infertility in Sertoli cell\u2010only syndrome: An investigation of autosomal gene defects"],"prefix":"10.1111","volume":"26","author":[{"given":"Gulsah","family":"Koc","sequence":"first","affiliation":[{"name":"Department of Medical Biology and Genetics Faculty of Medicine Istanbul Aydin University Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah A","family":"Ozdemir","sequence":"additional","affiliation":[{"name":"Department of Urology SBU Zeynep Kamil Women and Children's Diseases Education and Research Hospital Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gozde","family":"Girgin","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics Faculty of Medicine Marmara University Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cem","family":"Akbal","sequence":"additional","affiliation":[{"name":"Department of Urology Faculty of Medicine Acibadem University Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deniz","family":"Kirac","sequence":"additional","affiliation":[{"name":"Department of Medical Biology Faculty of Medicine Yeditepe University Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuba","family":"Avcilar","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics Faculty of Medicine Marmara University Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet I","family":"Guney","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics Faculty of Medicine Marmara University Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,11,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1016\/j.fertnstert.2009.09.009","article-title":"International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology","volume":"2009","author":"Zegers F","year":"2009","journal-title":"Fertil. 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