{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T17:45:31Z","timestamp":1773078331727,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T00:00:00Z","timestamp":1549929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To examine intraoperative and postoperative morbidity and mortality, as well as the impact on length of stay and total hospital charges of minimally invasive nephroureterectomy compared with open nephroureterectomy in patients with upper tract urothelial carcinoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Within the National Inpatient Sample (2008\u20132013), we identified patients with non\u2010metastatic upper tract urothelial carcinoma treated with either minimally invasive nephroureterectomy or open nephroureterectomy. We relied on inverse probability of treatment weighting to reduce the effect of inherent differences between open nephroureterectomy versus minimally invasive nephroureterectomy. Multivariable logistic regression, multivariable Poisson regression models and multivariable linear regression models were used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Between 2008 and 2013, we identified 3897 patients treated with either minimally invasive nephroureterectomy (1093 [28%]) or open nephroureterectomy (2804 [72%]). In multivariable logistic regression models, minimally invasive nephroureterectomy resulted in lower rates of overall (odds ratio 0.71,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001), wound (odds ratio 0.49,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.01), intraoperative (odds ratio 0.55,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.01), miscellaneous surgical (odds ratio 0.64,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.008) and miscellaneous medical complications (odds ratio 0.77,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.002). Furthermore, minimally invasive nephroureterectomy was associated with lower rates of transfusions (odds ratio 0.61,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). In multivariable Poisson regression models, minimally invasive nephroureterectomy was associated with shorter length of stay (relative risk 0.88,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). Finally, higher total hospital charges ($2500 more per patient) were recorded for minimally invasive nephroureterectomy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Intraoperative and postoperative morbidity, as well as length of stay, but not total hospital charges favor minimally invasive nephroureterectomy over open nephroureterectomy. These outcomes validate the safety and feasibility of minimally invasive nephroureterectomy in select upper tract urothelial carcinoma patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iju.13916","type":"journal-article","created":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T20:04:23Z","timestamp":1550001863000},"page":"487-492","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Comparison of perioperative outcomes between open and minimally invasive nephroureterectomy: A population\u2010based analysis"],"prefix":"10.1111","volume":"26","author":[{"given":"Sebastiano","family":"Nazzani","sequence":"first","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit University of Montreal Health Center Montreal Quebec Canada"},{"name":"Centre de recherche du Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al Institut du cancer de Montr\u00e9al Montreal Quebec Canada"},{"name":"Academic Department of Urology IRCCS Policlinico San Donato University of Milan Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Am\u00e9lie","family":"Bazinet","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit University of Montreal Health Center Montreal Quebec Canada"},{"name":"Centre de recherche du Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al Institut du cancer de Montr\u00e9al Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Preisser","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit University of Montreal Health Center Montreal Quebec Canada"},{"name":"Centre de recherche du Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al Institut du cancer de Montr\u00e9al Montreal Quebec Canada"},{"name":"Martini\u2010Klinik Prostate Cancer Center University Hospital Hamburg\u2010Eppendorf Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elio","family":"Mazzone","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit University of Montreal Health Center Montreal Quebec Canada"},{"name":"Centre de recherche du Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al Institut du cancer de Montr\u00e9al Montreal Quebec Canada"},{"name":"Division of Oncology\/Unit of Urology URI IRCCS Ospedale San Raffaele Vita\u2010Salute San Raffaele University Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe","family":"Tian","sequence":"additional","affiliation":[{"name":"Centre de recherche du Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al Institut du cancer de Montr\u00e9al Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco A","family":"Mistretta","sequence":"additional","affiliation":[{"name":"Department of Urology Istituto Europeo di Oncologia Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahrokh F","family":"Shariat","sequence":"additional","affiliation":[{"name":"Department of Urology Medical University of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred","family":"Saad","sequence":"additional","affiliation":[{"name":"Centre de recherche du Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al Institut du cancer de Montr\u00e9al Montreal Quebec Canada"},{"name":"Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al Center Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin C","family":"Zorn","sequence":"additional","affiliation":[{"name":"Centre de recherche du Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al Institut du cancer de Montr\u00e9al Montreal Quebec Canada"},{"name":"Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al Center Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Montanari","sequence":"additional","affiliation":[{"name":"Department of Urology IRCCS Fondazione Ca\u2019 Granda\u2010Ospedale Maggiore Policlinico University of Milan Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Briganti","sequence":"additional","affiliation":[{"name":"Division of Oncology\/Unit of Urology URI IRCCS Ospedale San Raffaele Vita\u2010Salute San Raffaele University Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Carmignani","sequence":"additional","affiliation":[{"name":"Academic Department of Urology IRCCS Policlinico San Donato University of Milan Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre I","family":"Karakiewicz","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit University of Montreal Health Center Montreal Quebec Canada"},{"name":"Centre de recherche du Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al Institut du cancer de Montr\u00e9al Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21442"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67019-X"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24147"},{"key":"e_1_2_7_5_1","unstructured":"Professionals S.\u2010O.Upper urinary tract urothelial cell carcinoma.Uroweb. 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