{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T16:02:34Z","timestamp":1777564954572,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T00:00:00Z","timestamp":1552867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine a follow\u2010up plan for mild congenital hydronephrosis in Japanese individuals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Neonates at Kansai Medical University Hospital (Hirakata, Osaka, Japan) who were diagnosed with mild congenital hydronephrosis \u2013 defined as a Society for Fetal Urology grade\u00a01 or 2 \u2013 at 1\u2010month old by abdominal ultrasonography between 2014 and 2016 were enrolled. These patients were encouraged to undergo repeated abdominal ultrasonography for 2\u00a0years every 3\u00a0months to investigate the course of congenital hydronephrosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 1009 neonates, congenital hydronephrosis was detected in 118 affected renal units of 100 (9.9%) patients. According to the definition of the Society for Fetal Urology, 118 affected renal units were graded as grade\u00a01 in 87 (74%), grade\u00a02 in 30 (25%), grade\u00a03 in one (1%) and grade\u00a04 in 0 units. Among them, 117 affected renal units of mild congenital hydronephrosis comprising grades\u00a01 and 2 were subjected to ultrasonographic evaluation to monitor the natural course. The rates of resolution at 7, 10, 13, 16, 19, 22 and 25 months after birth in Society for Fetal Urology grades 1 and 2 cases were 60% and 8%, 77% and 19%, 90% and 32%, 92% and 40%, 95% and 52%, 96% and 56%, and 99% and 60%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Grade\u00a01 congenital hydronephrosis does not need to be followed up, because it mostly shows spontaneous resolution by 2\u00a0years of follow up without any complications. However, ultrasonographic examinations at 1\u2010year intervals for grade\u00a02 congenital hydronephrosis are recommended to determine the subsequent follow\u2010up plan of patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.13948","type":"journal-article","created":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T02:59:07Z","timestamp":1552964347000},"page":"643-647","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Natural course of isolated mild congenital hydronephrosis: A 2\u2010year prospective study at a single center in Japan"],"prefix":"10.1111","volume":"26","author":[{"given":"Eriko","family":"Kohata","sequence":"first","affiliation":[{"name":"Department of Pediatrics Kansai Medical University Hirakata Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahisa","family":"Kimata","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kansai Medical University Hirakata Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chikushi","family":"Onuma","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kansai Medical University Hirakata Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohsaku","family":"Yamanouchi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kansai Medical University Hirakata Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoji","family":"Tsuji","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kansai Medical University Hirakata Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Ohashi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kansai Medical University Hirakata Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunari","family":"Kaneko","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kansai Medical University Hirakata Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(86)80204-4"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-0143(05)70005-7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-012-3258-4"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2010.02.205"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-0746-9"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-003-1287-x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000020795"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.03.032"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2014.07.004"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)00459-3"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.2003.04476.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)00933-X"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.03.065"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-306050"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-012-2113-0"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2011.06.009"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.3989"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2006.01.046"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2012.03476.x"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.03.107"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02012459"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-1330"},{"key":"e_1_2_8_24_1","first-page":"1","article-title":"Guidelines on paediatric urology","author":"Tekgul S","year":"2013","journal-title":"Eur. 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