{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T07:12:33Z","timestamp":1779001953817,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T00:00:00Z","timestamp":1554249600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the long\u2010term efficacy of electrofulguration in women with recurrent urinary tract infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>After institutional review board approval, a retrospective study of women who underwent electrofulguration alone was carried out. All patients had recurrent urinary tract infections defined as three or more urinary tract infections\/year, and a preoperative office cystoscopy showing inflammatory lesions, categorized by location: urethra, bladder neck, trigone and beyond the trigone. All lesions were cauterized during outpatient electrofulguration under anesthesia. On 6\u2010month postoperative office cystoscopy, endoscopic success was defined as resolution of all lesions previously seen and no new lesions. The primary outcome was urinary tract infections\/year, with urinary tract infection defined as antibiotic treatment for urinary tract infection\u2010like symptoms and\/or for positive urine culture. Clinical cure was defined as no further urinary tract infections, clinical improvement as less than three urinary tract infections\/year, and clinical failure as three or more urinary tract infections\/year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 95 women who met the study criteria between 2004 and 2016, 62 (65%) were endoscopically successful, and 33 (35%) were endoscopic failures based on postoperative cystoscopy. Among all patients, over a median follow\u2010up period of 4.9\u00a0years, the median number of urinary tract infections\/year was 0.8. Endoscopically successful patients had fewer urinary tract infections\/year compared with endoscopic failures (0.6 <jats:italic>vs<\/jats:italic> 0.9, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.03). Clinically, 14 (15%) patients were cured, 69 (73%) were improved and 12 (13%) failed. Compared with clinically improved patients, clinical failures were more likely to have infections with multiple organisms (92% <jats:italic>vs<\/jats:italic> 35%, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001) and highly resistant organisms (92% <jats:italic>vs<\/jats:italic> 23%, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In our experience, nearly two\u2010thirds of women with recurrent urinary tract infection can be successfully treated with electrofulguration, and &gt;80% experience long\u2010term clinical cure or improvement in urinary tract infections.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.13963","type":"journal-article","created":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T23:59:50Z","timestamp":1554335990000},"page":"662-668","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Electrofulguration in the advanced management of antibiotic\u2010refractory recurrent urinary tract infections in women"],"prefix":"10.1111","volume":"26","author":[{"given":"Joseph J","family":"Crivelli","sequence":"first","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feras","family":"Alhalabi","sequence":"additional","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe E","family":"Zimmern","sequence":"additional","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(02)01054-9"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/22.1.91"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/14737167.2017.1359543"},{"key":"e_1_2_8_5_1","first-page":"237","volume-title":"Campbell\u2010Walsh Urology","author":"Schaeffer AJ","year":"2016"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.01.111"},{"key":"e_1_2_8_7_1","unstructured":"BonkatG PickardR BartolettiRet\u00a0al.EAU guidelines on urological infections.2017. 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