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Although renal transplantation is greatly beneficial for most patients with end\u2010stage kidney disease, many of these patients must remain on dialysis therapy for extended periods due to the scarcity of organs from deceased donors. ABO blood type incompatibility was once believed to be a contraindication to renal transplantation due to the increased risk for antibody\u2010mediated rejection and early graft loss attributable to isoagglutinins. Recently, pretransplant desensitization strategies, such as removal of isoagglutinins and antibody\u2010producing cells, have achieved successful outcomes, although it remains unclear whether graft survival and patient morbidity are equivalent to those for ABO\u2010compatible renal transplantation. The present review suggested that ABO\u2010incompatible living\u2010donor renal transplantation might be a favorable radical renal replacement therapy for patients with end\u2010stage kidney disease.<\/jats:p>","DOI":"10.1111\/iju.14109","type":"journal-article","created":{"date-parts":[[2019,9,15]],"date-time":"2019-09-15T01:30:22Z","timestamp":1568511022000},"page":"30-38","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Latest insights on ABO\u2010incompatible living\u2010donor renal transplantation"],"prefix":"10.1111","volume":"27","author":[{"given":"Junji","family":"Uchida","sequence":"first","affiliation":[{"name":"Department of Urology Osaka City University Graduate School of Medicine Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Kosoku","sequence":"additional","affiliation":[{"name":"Department of Urology Osaka City University Graduate School of Medicine Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihide","family":"Naganuma","sequence":"additional","affiliation":[{"name":"Department of Urology Osaka City University Graduate School of Medicine Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoaki","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Urology Suita Municipal Hospital Suita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuya","family":"Nakatani","sequence":"additional","affiliation":[{"name":"Department of Urology Osaka City University Graduate School of Medicine Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,14]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198502283120905"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199912023412303"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41100-016-0080-9"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14124"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI103085"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(63)90292-7"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)64510-5"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00464.x"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31819f2024"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfv388"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13502"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0208638"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32091-9"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e318245b2af"},{"key":"e_1_2_14_16_1","first-page":"4549","article-title":"ABO incompatibility in cadaver donor kidney allografts","volume":"19","author":"Cook DJ","year":"1987","journal-title":"Transplant. 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