{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:25:46Z","timestamp":1791840346242,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T00:00:00Z","timestamp":1589846400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the use of human amniotic membrane allograft to prevent urethrocutaneous fistula after tubularized incised plate repair for redo\u2010hypospadias and anterior urethral defects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This pilot study included 28 patients (mean age 25.3\u00a0\u00b1\u00a011\u00a0years) with a history of previous failed hypospadia repair, who underwent tubularized incised plate urethroplasty in one session by the same surgical team from April 2016 to April 2019. After the reconstruction of a neourethra and proper hemostasis, a human amniotic membrane allograft \u2013 Grafting Scaffold \u2013 was used to cover the suture lines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean follow\u2010up time was 13.3\u00a0\u00b1\u00a04.5\u00a0months. Two urethrocutaneous fistulas occurred within the first 2\u00a0weeks after the surgery, one of which was caused by the infection of the surgical site. No penile torsion, urethral diverticula, meatal stenosis or glans dehiscence was reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Amniotic membrane graft provides an applicable, low\u2010cost, feasible, biodegradable and safe second cover in redo\u2010hypospadias repairs by tubularized incised plate technique. Its use is technically easy; it has satisfactory cosmetic outcomes and might decrease urethrocutaneous fistula formation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.14257","type":"journal-article","created":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T01:14:30Z","timestamp":1589937270000},"page":"605-609","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Use of human amniotic membrane repair of anterior urethral defect: First clinical report"],"prefix":"10.1111","volume":"27","author":[{"given":"Mohammadreza","family":"Razzaghi","sequence":"first","affiliation":[{"name":"Laser Application in Medical Science Research Center Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amirhossein","family":"Rahavian","sequence":"additional","affiliation":[{"name":"Clinical Research Development Unit Shohada\u2010e\u2010Tajrish Hospital Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morteza","family":"Fallah Karkan","sequence":"additional","affiliation":[{"name":"Laser Application in Medical Science Research Center Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzad","family":"Allameh","sequence":"additional","affiliation":[{"name":"Center of Excellence for Training Laser Applications in Medicine Shohada\u2010e\u2010Tajrish Hospital Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saleh","family":"Ghiasy","sequence":"additional","affiliation":[{"name":"Clinical Research Development Unit Shohada\u2010e\u2010Tajrish Hospital Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babak","family":"Javanmard","sequence":"additional","affiliation":[{"name":"Clinical Research Development Unit Shohada\u2010e\u2010Tajrish Hospital Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,19]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"3399","volume-title":"Campbell\u2010Walsh Urology","author":"Snodgrass WT","year":"2016"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)32697-6"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2015.04.105"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2017.09.01"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.12092"},{"key":"e_1_2_8_7_1","doi-asserted-by":"crossref","first-page":"e0118653","DOI":"10.1371\/journal.pone.0118653","article-title":"Tissue engineering for human urethral reconstruction: systematic review of recent literature","volume":"10","author":"Kemp V","year":"2015","journal-title":"PLoS One"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12035"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)63293-2"},{"key":"e_1_2_8_10_1","first-page":"49","article-title":"Causes, presentation and survival of fifty\u2010seven patients with necrotizing fasciitis of the male genitalia","volume":"170","author":"Clayton M","year":"1990","journal-title":"Surg. 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