{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:52:22Z","timestamp":1787014342251,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T00:00:00Z","timestamp":1595548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the impact of smoking and the benefit of smoking cessation on lower urinary tract function and prostatic inflammation in patients with benign prostatic hyperplasia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The medical records of 118 benign prostatic hyperplasia patients who underwent transurethral prostatic surgery between 2006 and 2016 were analyzed. Their smoking history was confirmed. The relationship between smoking and main clinical parameters, International Prostate Symptom Scores, uroflowmetry, pressure flow study, magnitude of prostatic inflammation and the level of serum C\u2010reactive protein was investigated. Furthermore, the relationships between smoking cessation and these clinical parameters were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The International Prostate Symptom Scores for straining among the non\u2010smokers were significantly lower than those of the smokers (1.71\n                      <jats:italic>vs<\/jats:italic>\n                      2.60,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0= 0.029). In the pressure flow study, there were negative correlations between the duration of smoking and strong desire to void (correlation coefficient \u22120.314,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.013), urgency (correlation coefficient \u22120.349,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.008) and bladder volume at initial detrusor overactivity (correlation coefficient \u22120.417,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.021). The duration of smoking cessation was negatively correlated with the magnitude of chronic prostatic inflammation (correlation coefficient \u22120.253,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.027). In the pressure flow study, the duration of smoking cessation was positively correlated with urgency (correlation coefficient 0.286,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.030) and maximum cystometric capacity (correlation coefficient 0.241,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.050).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Smoking could be a risk factor for the exacerbation of storage dysfunction in benign prostatic hyperplasia patients. Smoking cessation is effective in improving chronic prostatic inflammation and storage dysfunction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iju.14320","type":"journal-article","created":{"date-parts":[[2020,7,25]],"date-time":"2020-07-25T02:20:11Z","timestamp":1595643611000},"page":"874-881","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Duration of smoking cessation is negatively associated with the magnitude of chronic prostatic inflammation and storage dysfunction in patients with benign prostatic hyperplasia"],"prefix":"10.1111","volume":"27","author":[{"given":"So","family":"Inamura","sequence":"first","affiliation":[{"name":"Departments of Department of Urology Faculty of Medical Sciences University of Fukui Eiheiji Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Ito","sequence":"additional","affiliation":[{"name":"Departments of Department of Urology Faculty of Medical Sciences University of Fukui Eiheiji Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Oe","sequence":"additional","affiliation":[{"name":"Departments of Department of Urology Faculty of Medical Sciences University of Fukui Eiheiji Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Seki","sequence":"additional","affiliation":[{"name":"Departments of Department of Urology Faculty of Medical Sciences University of Fukui Eiheiji Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minekatsu","family":"Taga","sequence":"additional","affiliation":[{"name":"Departments of Department of Urology Faculty of Medical Sciences University of Fukui Eiheiji Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motohiro","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Tumor Pathology Faculty of Medical Sciences University of Fukui Eiheiji Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Departments of Department of Urology Faculty of Medical Sciences University of Fukui Eiheiji Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2703"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2016.03.001"},{"key":"e_1_2_7_4_1","volume-title":"The health consequences of smoking\u201450 years of progress: A report of the Surgeon General","author":"US Department of Health and Human Services","year":"2014"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI62839"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S82259"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1211128"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3826"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)70266-9"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2004.00791.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.07813.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2004.04839.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009775"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.03.128"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-017-0003-z"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200012143432406"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199805000-00046"},{"key":"e_1_2_7_18_1","first-page":"684","article-title":"The effect of bronchitis, smoking, and occupation on ventilation","volume":"87","author":"Brinkman GL","year":"1963","journal-title":"Am. 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