{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:24:01Z","timestamp":1773282241891,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T00:00:00Z","timestamp":1611187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To report our experience with ureterolysis for the management of retroperitoneal fibrosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The data of 25 patients who underwent ureterolysis due to primary retroperitoneal fibrosis between 2002 and 2017 were reviewed retrospectively. Initial symptoms, laterality, renal function status (initial\/final), operation complications and serum creatinine levels (diagnosis\/preoperative\/6\u00a0months, 12\u00a0months postoperatively) were recorded. After surgery, patients were followed up by ultrasonography and serum creatinine levels. Patients with impaired results underwent furosemide renogram and\/or late phase of computed tomography. Factors affecting final serum creatinine levels were evaluated. The \u03c7<jats:sup>2<\/jats:sup>\u2010test was used for nominal data among groups. The level of statistical significance was set as <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 19 patients (76%) were operated bilaterally. The mean follow\u2010up period was 46.2\u00a0\u00b1\u00a09.2\u00a0months. Among 44 operated renal units, non\u2010functioning kidney developed in seven (15.9%). A total of 34 renal units (77.3%) did not require any additional surgical intervention, and two underwent balloon dilatation (4.5%), one (2.25%) followed with double J stent changes. Two patients developed end\u2010stage renal disease secondary to bilateral unresolved obstruction. High final serum creatinine levels developed in eight (32%) patients without dialysis. Eight patients (32%) were treated with immunosuppressive therapy for systemic recurrence. There was a significant relationship between preoperative serum creatinine levels with final serum creatinine levels (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.005). There was no statistically significant relationship between diagnosis serum creatinine levels with final serum creatinine levels and postoperative dialysis requirement (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.79 and <jats:italic>P<\/jats:italic>\u00a0=\u00a00.817, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Ureterolysis provides acceptable success with low complication rates in patients with retroperitoneal fibrosis. Preoperative high\u2010serum creatinine levels can be considered as a risk factor for long\u2010term renal impairment and these patients should be followed closely.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.14496","type":"journal-article","created":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T00:48:01Z","timestamp":1611276481000},"page":"520-525","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Outcomes of ureterolysis for primary retroperitoneal fibrosis: A single\u2010center experience"],"prefix":"10.1111","volume":"28","author":[{"given":"Ali Cansu","family":"Bozaci","sequence":"first","affiliation":[{"name":"Department of Urology Hacettepe University School of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mesut","family":"Altan","sequence":"additional","affiliation":[{"name":"Department of Urology Hacettepe University School of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan Bahadir","family":"Haberal","sequence":"additional","affiliation":[{"name":"Department of Urology Hacettepe University School of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emrullah","family":"S\u00f6\u011f\u00fctdelen","sequence":"additional","affiliation":[{"name":"Department of Urology Hacettepe University School of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fazil Tuncay","family":"Aki","sequence":"additional","affiliation":[{"name":"Department of Urology Hacettepe University School of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130lhan","family":"Erkan","sequence":"additional","affiliation":[{"name":"Department of Urology Hacettepe University School of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-857X(05)70260-X"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2017.1290911"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000473218"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cccn.2004.02.007"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68035-5"},{"key":"e_1_2_7_7_1","first-page":"392","article-title":"Periaortitis heralding Wegener's granulomatosis","volume":"29","author":"Serratrice J","year":"2002","journal-title":"J. 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