{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T23:36:15Z","timestamp":1792366575052,"version":"4.4.0"},"reference-count":15,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To provide a detailed step\u2010by\u2010step operative technique, and to report on long\u2010term functional and metabolic outcomes in secondary continence mechanisms in the form of secondary intussuscepted ileal nipple valves in revisional surgery of ileocecal pouches.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From May 1997 to May 2015, 18 female and 10 male patients suffering from dysfunctional primary continence mechanisms of their ileocecal pouch underwent revisonal surgery to create a secondary ileal nipple valve at our tertiary referral center. The average follow\u2010up period was 65.4\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After surgery, 24 patients were continent by day and night, and four patients showed minor incontinence with the use of a safety pad. The average frequency of clean intermittent catheterization decreased both during the day and at night. The diameter of the catheters used for clean intermittent catheterization increased significantly. No patient showed stomal stenosis, change of stool habits or metabolic situation in the follow\u2010up period. Furthermore, the creation of the secondary ileal nipple valves did not affect the capacity of the reservoir. In the long\u2010term follow up, two patients required the construction of a third continence mechanism, making for an overall success rate of 92% in the study group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>To our knowledge, this is the first study of long\u2010term results after the creation of secondary ileal nipple valves. We provide evidence that the creation of a secondary ileal nipple valve is a safe and reliable procedure for continence restoration in ileocecal pouches with excellent functional and metabolic long\u2010term outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.14654","type":"journal-article","created":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T07:06:43Z","timestamp":1630480003000},"page":"1105-1111","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Troubleshooting of failed continence mechanisms in the ileocecal pouch: Operative technique and long\u2010term results of the intussuscepted ileal nipple valve"],"prefix":"10.1111","volume":"28","author":[{"given":"Charis","family":"Kalogirou","sequence":"first","affiliation":[{"name":"Department of Urology and Pediatric Urology University Medical Center of W\u00fcrzburg W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Schwinger","sequence":"additional","affiliation":[{"name":"Department of Urology and Pediatric Urology University Medical Center of W\u00fcrzburg W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arkadius","family":"Kocot","sequence":"additional","affiliation":[{"name":"Department of Urology and Pediatric Urology University Medical Center of W\u00fcrzburg W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubertus","family":"Riedmiller","sequence":"additional","affiliation":[{"name":"Department of Urology and Pediatric Urology University Medical Center of W\u00fcrzburg W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)44714-8"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-006-0078-y"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)64315-5"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)40200-X"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)61769-5"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199502000-00004"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.07.052"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)66213-1"},{"key":"e_1_2_8_10_1","first-page":"66","article-title":"Hydraulic valve for continence and antireflux. 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