{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:38:12Z","timestamp":1790815092436,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T00:00:00Z","timestamp":1655337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Overactive bladder (OAB) is identified as a urinary urgency accompanied by frequency and nocturia with or without urgency urinary incontinence in the nonexistence of a urinary tract infection or other evident pathologies. This systematic review and meta\u2010analysis aimed to evaluate the efficacy of the transcutaneous tibial nerve stimulation (TTNS) versus percutaneous tibial nerve stimulation (PTNS) or anticholinergic drugs in reducing symptoms and improving the quality of life for OAB patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a systematic search in Medline, Embase, and CENTRAL, in which we included randomized controlled trials that compared TTNS with anticholinergic drugs or PTNS in treating idiopathic OAB. We evaluated the following outcomes: 3\u2010day voiding diary (voiding frequency\/day, daytime micturition frequency\/day, nighttime micturition frequency\/day, number of urgency episodes\/day, number of incontinence episodes\/day, and mean voiding volume), symptom bother, health related quality of life (HRQoL), and adverse events. We used 95% as a confidence interval (CI) and <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05. Standardized mean difference (SMD) was used for continuous outcomes, and the risk ratio (RR) was used for dichotomous outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no significant difference comparing TTNS with anticholinergic drugs or PTNS regarding voiding frequency\/day (SMD\u2009=\u2009\u22120.01, 95% CI \u22120.33 to 0.32), nighttime micturition frequency\/day (SMD\u2009=\u2009\u22120.28, 95% CI \u22120.94 to 0.37), number of urgency episodes\/day (SMD\u2009=\u2009\u22120.05, 95% CI \u22120.36 to 0.26), number of incontinence episodes\/day (SMD\u2009=\u2009\u22120.04, 95% CI \u22120.32 to 0.25), symptom bother (SMD\u2009=\u2009\u22120.19, 95% CI \u22120.55 to 0.16), HRQoL (SMD\u2009=\u20090.27, 95% CI \u22120.32 to 0.85), and adverse events (RR\u2009=\u20090.07, 95% CI 0.01 to 0.54).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The current meta\u2010analysis reveals that there is no statistically significant difference between TTNS versus PTNS or anticholinergic drugs for the nonsurgical management of OAB patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.14961","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T01:33:21Z","timestamp":1655429601000},"page":"1170-1180","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Non\u2010inferior and more feasible transcutaneous tibial nerve stimulation in treating overactive bladder: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6004-8335","authenticated-orcid":false,"given":"Mohammed S","family":"Alomari","sequence":"first","affiliation":[{"name":"College of Medicine King Saud bin Abdulaziz University for Health Sciences  Jeddah Saudi Arabia"},{"name":"King Abdullah International Medical Research Center  Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed S","family":"Abdulhamid","sequence":"additional","affiliation":[{"name":"College of Medicine King Saud bin Abdulaziz University for Health Sciences  Jeddah Saudi Arabia"},{"name":"King Abdullah International Medical Research Center  Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah A","family":"Ghaddaf","sequence":"additional","affiliation":[{"name":"College of Medicine King Saud bin Abdulaziz University for Health Sciences  Jeddah Saudi Arabia"},{"name":"King Abdullah International Medical Research Center  Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid M","family":"Alshareef","sequence":"additional","affiliation":[{"name":"College of Medicine King Saud bin Abdulaziz University for Health Sciences  Jeddah Saudi Arabia"},{"name":"King Abdullah International Medical Research Center  Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed K","family":"Haneef","sequence":"additional","affiliation":[{"name":"College of Medicine King Saud bin Abdulaziz University for Health Sciences  Jeddah Saudi Arabia"},{"name":"King Abdullah International Medical Research Center  Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad S","family":"AlQuhaibi","sequence":"additional","affiliation":[{"name":"College of Medicine King Saud bin Abdulaziz University for Health Sciences  Jeddah Saudi Arabia"},{"name":"King Abdullah International Medical Research Center  Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rowaa A","family":"Banjar","sequence":"additional","affiliation":[{"name":"Department of Urology King Abdulaziz Medical City, National Guard Health Affairs  Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,16]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2015.01.087"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2010.09993.x"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2012.04.004"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2010.05422.x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-013-1112-5"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31818e8aa4"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/03000605211042994"},{"key":"e_1_2_12_9_1","unstructured":"NICE.Urinary incontinence and pelvic organ prolapse in women: management.2021[cited 2021 Sep 22]. 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