{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T19:15:42Z","timestamp":1787253342508,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Transurethral resection of bladder tumors (TURBT) surgeries requires post\u2010resection catheterization for continuous irrigation of the bladder. This indwelling catheter is associated with distressing catheter\u2010related bladder discomfort (CRBD) and increases postoperative pain and agitation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To prove the hypothesis that transurethral 100\u2009mg lidocaine irrigation at the end of TURBT can reduce the frequency of moderate\u2010to\u2010severe postoperative CRBD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>116 patients scheduled for TURBT were screened, 94 were recruited and completed the study. American Society of Anesthesiologists Physical Status I\u2013II adult patients, 20\u201375\u2009years of age undergoing elective TURBT surgery under general anesthesia were included. Transurethral normal saline with 0.01% lidocaine (100\u2009mg in 1\u2009L NS) was used for irrigation 30\u00a0min before the completion of surgery in group L, while only normal saline was used for transurethral irrigation in group N. The main outcomes were frequency of CRBD, pain and patient satisfaction at 0, 1, 2, and 6\u00a0h postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 94 patients were analyzed in the study. The incidence of moderate\u2013severe CRBD was significantly lower in group L as compared to group C at 0, 1, and 2\u00a0h (65.9% vs. 31.9%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.01; 31.9% vs. 10.6%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.012; 21.3% vs. 2.1%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.004, respectively). At the 6\u2010h mark, the incidence of CRBD was lower in group L, although this did not achieve statistical significance (6.38% vs. 2.1%; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.613).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Irrigation with 0.01% lidocaine (100\u2009mg) towards the end of TURBT reduces the incidence of moderate\u2013severe CRBD by 52% and increases patient satisfaction.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.15100","type":"journal-article","created":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T20:19:05Z","timestamp":1668457145000},"page":"264-270","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Transurethral lidocaine (100\u2009mg) bladder irrigation (TULI100) reduces the incidence of catheter related bladder discomfort in transurethral resection of bladder tumors: A randomized, double blind, controlled 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