{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T16:25:49Z","timestamp":1783700749037,"version":"3.55.0"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:00:00Z","timestamp":1672099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to investigate the utility of uroflowmetry in predicting anatomical success following urethroplasty based on real\u2010world clinical data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 100 male patients who underwent urethroplasty for urethral strictures at our institute were analyzed. Postoperative anatomical success was determined as the passage of a 16.2 Fr flexible endoscope after approximately 4\u00a0months following the procedure. Sensitivity and specificity of the maximal flow rate (<jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub>), average flow rate (<jats:italic>Q<\/jats:italic><jats:sub>ave<\/jats:sub>), and <jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub>\u2009\u2212\u2009<jats:italic>Q<\/jats:italic><jats:sub>ave<\/jats:sub> for anatomical success were determined, along with receiver operating characteristic analysis. The optimal cutoff was set using Youden's index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Anatomical success was observed in 67%. Voided volumes in the success and failure groups were equivalent: 252\u2009\u00b1\u2009121 versus 242\u2009\u00b1\u200991\u2009ml, respectively. In 18 cases, voided volumes were &lt;150\u2009ml. Parameters of uroflowmetry were all significantly higher in the anatomical success group when compared to those in the failure group: the mean value of <jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub> was 26.1 versus 15.0\u00a0ml\/s; <jats:italic>Q<\/jats:italic><jats:sub>ave<\/jats:sub>, 14.2 versus 9.1\u00a0ml\/s; and <jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub>\u2009\u2212\u2009<jats:italic>Q<\/jats:italic><jats:sub>ave<\/jats:sub>, 11.9 versus 5.9\u00a0ml\/s, respectively (<jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.0001 for each parameter). The area under the curve was 0.8082 for <jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub>, 0.7727 for <jats:italic>Q<\/jats:italic><jats:sub>ave<\/jats:sub>, and 0.8186 for <jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub>\u2009\u2212\u2009<jats:italic>Q<\/jats:italic><jats:sub>ave<\/jats:sub>. Optimal cutoff values for <jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub> and <jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub>\u2009\u2212\u2009<jats:italic>Q<\/jats:italic><jats:sub>ave<\/jats:sub> were 20 and 6\u2009ml\/s, which predicted anatomical success with 86% and 87% positive predictive value, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This analysis presents statistically valid cutoffs by which uroflowmetry can be used as a viable surrogate of anatomical success following urethroplasty in clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.15137","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T07:25:03Z","timestamp":1672212303000},"page":"390-394","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Uroflowmetry is a viable surrogate for urethroscopy in evaluation of anatomical success following urethroplasty"],"prefix":"10.1111","volume":"30","author":[{"given":"Toeki","family":"Yanagi","sequence":"first","affiliation":[{"name":"Department of Urology Hyogo Medical University  Nishinomiya Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0669-8986","authenticated-orcid":false,"given":"Akihiro","family":"Kanematsu","sequence":"additional","affiliation":[{"name":"Department of Urology Hyogo Medical University  Nishinomiya Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimihiro","family":"Shimatani","sequence":"additional","affiliation":[{"name":"Department of Urology Hyogo Medical University  Nishinomiya Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Urology Hyogo Medical University  Nishinomiya Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,27]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2021.05.032"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2012.10.046"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.01.054"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.06.015"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.12.070"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-9056(17)31174-0"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bimj.200410135"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.13730"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.07.010"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000002353"}],"container-title":["International Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iju.15137","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/iju.15137","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iju.15137","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T01:38:33Z","timestamp":1697074713000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iju.15137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,27]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1111\/iju.15137"],"URL":"https:\/\/doi.org\/10.1111\/iju.15137","archive":["Portico"],"relation":{},"ISSN":["0919-8172","1442-2042"],"issn-type":[{"value":"0919-8172","type":"print"},{"value":"1442-2042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,27]]},"assertion":[{"value":"2022-08-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}