{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T18:26:18Z","timestamp":1783967178057,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T00:00:00Z","timestamp":1690761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To preoperative factors that could predict the persisting storage symptoms after Holmium laser enucleation of the prostate (HoLEP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records of 257 patients who underwent HoLEP between December 2014 and January 2021 were reviewed. Participants with a follow\u2010up period exceeding 6\u2009months were included. Preoperative data, including International Prostate Symptom Score (IPSS), uroflowmetry, prostate size, and prostate\u2010specific antigen, were collected. All participants underwent a preoperative urodynamic study. The correlation between perioperative variables and postoperative medication therapy (antimuscarinics or beta\u20103 agonists) was assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 257 participants in the study, 46 (18.6%) were allocated to the medication group, of which 25 (54.3%) initiated medication therapy postoperatively. The medication group showed worse postoperative IPSS storage symptom score and quality of life score compared to the medication\u2010free group (<jats:italic>p<\/jats:italic>\u2009=\u20090.048 and <jats:italic>p<\/jats:italic>\u2009=\u20090.002, respectively), but no significant differences were observed in complications or operative variables. In the de\u2010novo medication group, patients had lower preoperative <jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub>, larger prostate volume, and smaller maximum cystometric capacity (MCC) compared to the persisting medication group (<jats:italic>p<\/jats:italic>\u2009=\u20090.020, <jats:italic>p<\/jats:italic>\u2009=\u20090.009, and <jats:italic>p<\/jats:italic>\u2009=\u20090.008, respectively). Overactive bladder (OAB) history, terminal detrusor overactivity (DO), and IPSS urgency item were identified as possible predictive factors for post\u2010HoLEP medication use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Preoperative factors such as OAB history, terminal DO, and IPSS urgency item may predict the need for post\u2010HoLEP medication therapy. Further follow\u2010up studies are warranted to understand the characteristics of the de\u2010novo medication group due to the significant discomfort it can cause to patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.15260","type":"journal-article","created":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T11:55:15Z","timestamp":1690804515000},"page":"1036-1043","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Predictive factors for postoperative medication therapy for overactive bladder symptoms after holmium laser enucleation of prostate"],"prefix":"10.1111","volume":"30","author":[{"given":"Sung Jin","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Urology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Gon","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Urology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahyun","family":"Pak","sequence":"additional","affiliation":[{"name":"Department of Urology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ohseong","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Urology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Goo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4691-6159","authenticated-orcid":false,"given":"Sung Tae","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Urology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,31]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.24846"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.5213\/inj.2142370.185"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000000309"},{"key":"e_1_2_13_5_1","first-page":"184","article-title":"Functional outcomes and complications following B\u2010TURP versus HoLEP for the treatment of benign prostatic hyperplasia: a review of the literature and meta\u2010analysis","volume":"20","author":"Qian X","year":"2017","journal-title":"Aging Male"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.12.038"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101615"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2012.0505"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2021.04.019"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2007.01491.x"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.10066"},{"key":"e_1_2_13_12_1","first-page":"S14","article-title":"Pressure flow urodynamic studies: the gold standard for diagnosing bladder outlet obstruction","volume":"7","author":"Nitti VW","year":"2005","journal-title":"Rev Urol"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2013.10.037"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2019.05.003"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.07.019"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.12482"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000357626"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-014-1424-0"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-44686-2"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-020-03126-x"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2006.06735.x"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)63949-3"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.12538"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.21201"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.4111\/kju.2014.55.1.47"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.12308"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2018.03.130"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.12.095"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.03.033"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.5213\/inj.2142046.023"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmhg.2005.01.007"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365597809179978"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.5213\/inj.1632534.267"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.5213\/inj.1832554.277"}],"container-title":["International Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iju.15260","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T16:26:25Z","timestamp":1698855985000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iju.15260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,31]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1111\/iju.15260"],"URL":"https:\/\/doi.org\/10.1111\/iju.15260","archive":["Portico"],"relation":{},"ISSN":["0919-8172","1442-2042"],"issn-type":[{"value":"0919-8172","type":"print"},{"value":"1442-2042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,31]]},"assertion":[{"value":"2023-04-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}