{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T19:59:06Z","timestamp":1780084746680,"version":"3.54.0"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T00:00:00Z","timestamp":1701129600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess whether 5\u2010year overall survival (OS) of squamous cell carcinoma of the penis (SCCP) patients differs from age\u2010matched male population\u2010based controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We relied on the Surveillance Epidemiology and End Results database (2004\u20132018) to identify newly diagnosed (2004\u20132013) SCCP patients. For each case, we simulated an age\u2010matched control (Monte Carlo simulation), relying on the Social Security Administration (SSA) Life Tables with 5\u2009years of follow\u2010up. We compared OS between SCCP patients and population\u2010based controls in a stage\u2010specific fashion. Smoothed cumulative incidence plots displayed cancer\u2010specific mortality (CSM) versus other\u2010cause mortality (OCM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 2282 SCCP patients, the stage distribution was as follows: stage I 976 (43%) versus stage II 826 (36%) versus stage III 302 (13%) versus stage IV 178 (8%). At 5\u2009years, OS of SCCP patients versus age\u2010matched population\u2010based controls was as follows: stage I 63% versus 80% (\u0394\u2009=\u200917%), stage II 50% versus 80% (\u0394\u2009=\u200930%), stage III 39% versus 84% (\u0394\u2009=\u200945%), stage IV 26% versus 87% (\u0394\u2009=\u200961%). At 5\u2009years, CSM versus OCM in SCCP patients according to stage was as follows: stage I 12% versus 24%, stage II 22% versus 28%, stage III 47% versus 14%, and stage IV 60% versus 14%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>SCCP patients exhibit worse OS across all stages. The difference in OS at 5\u2009years between SCCP and age\u2010matched male population\u2010based controls ranged from 17% to 61%. At 5\u2009years, CSM accounted for 12% to 60% of all deaths, across all stages.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.15346","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T13:30:19Z","timestamp":1701178219000},"page":"274-279","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Differences in overall survival of penile cancer patients versus population\u2010based controls"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2036-8438","authenticated-orcid":false,"given":"Lukas","family":"Scheipner","sequence":"first","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Urology Medical University of Graz  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9712-2685","authenticated-orcid":false,"given":"Stefano","family":"Tappero","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Urology IRCCS Policlinico San Martino  Genova Italy"},{"name":"Department of Surgical and Diagnostic Integrated Sciences (DISC) University of Genova  Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattia Luca","family":"Piccinelli","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Urology IEO European Institute of Oncology, IRCCS  Milan Italy"},{"name":"Universit\u00e0 degli Studi di Milano  Milan 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Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reha\u2010Baris","family":"Incesu","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Martini\u2010Klinik Prostate Cancer Center University Hospital Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5340-8569","authenticated-orcid":false,"given":"Simone","family":"Morra","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Neurosciences, Science of Reproduction and Odontostomatology University of Naples Federico II  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Tian","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Saad","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahrokh F.","family":"Shariat","sequence":"additional","affiliation":[{"name":"Department of Urology, Comprehensive Cancer Center Medical University of Vienna  Vienna Austria"},{"name":"Department of Urology Weill Cornell Medical College  New York New York USA"},{"name":"Department of Urology University of Texas Southwestern  Dallas Texas USA"},{"name":"Hourani Center for Applied Scientific Research Al\u2010Ahliyya Amman University  Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Terrone","sequence":"additional","affiliation":[{"name":"Department of Urology IRCCS Policlinico San Martino  Genova Italy"},{"name":"Department of Surgical and Diagnostic Integrated Sciences (DISC) University of Genova  Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ottavio","family":"De Cobelli","sequence":"additional","affiliation":[{"name":"Department of Urology IEO European Institute of Oncology, IRCCS  Milan Italy"},{"name":"Department of Oncology and Haemato\u2010Oncology Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Briganti","sequence":"additional","affiliation":[{"name":"Soldera Prostate Cancer Lab, Unit of Urology\/Division of Oncology, Gianfranco IRCCS San Raffaele Scientific Institute  Milan 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H.","family":"Chun","sequence":"additional","affiliation":[{"name":"Vita\u2010Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7033-1380","authenticated-orcid":false,"given":"Derya","family":"Tilki","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt Goethe University Frankfurt am Main  Frankfurt am Main Germany"},{"name":"Department of Urology University Hospital Hamburg\u2010Eppendorf  Hamburg Germany"},{"name":"Department of Urology Koc University Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Longo","sequence":"additional","affiliation":[{"name":"Martini\u2010Klinik Prostate Cancer Center University Hospital Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Seles","sequence":"additional","affiliation":[{"name":"Department of Urology Medical University of Graz  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sascha","family":"Ahyai","sequence":"additional","affiliation":[{"name":"Department of Urology Medical University of Graz  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre I.","family":"Karakiewicz","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,28]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"Social Security Administration.Actuarial life table [Internet]. 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