{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T06:06:53Z","timestamp":1785391613086,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T00:00:00Z","timestamp":1704240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the incidence of surgical site infections (SSI) between robot\u2010assisted and open radical cystectomies and investigate the risk factors for SSI after radical cystectomies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients who underwent radical cystectomy between July 2008 and December 2022 were retrospectively reviewed. The prevalence and characteristics of SSI after open and robot\u2010assisted radical cystectomies were compared, and the risk factors for SSI were investigated using propensity score matching.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study enrolled 231 patients (open: 145, robot\u2010assisted: 86). In the robot\u2010assisted group, urinary diversion was performed using an intracorporeal approach. SSI occurred in 34 (open: 28, robot\u2010assisted: 6) patients, and the incidence was significantly lower in the robot\u2010assisted group (19.3% vs. 7.0%, <jats:italic>p<\/jats:italic>\u2009=\u20090.007). After propensity score matching cohort (open: 34, robot\u2010assisted: 34), increased bleeding volume, blood transfusion, and delayed postoperative oral feeding were significantly associated with SSI. Only increased bleeding volume remained a significant risk factor in the multivariate regression analysis (odds ratio, 1.13 [per 100\u2009mL increase]; 95% confidence interval: 1.02\u20131.25; <jats:italic>p<\/jats:italic>\u2009=\u20090.001). The cutoff bleeding volume for predicting SSI was 1630\u2009mL with an area under the receiver operating characteristic curve, sensitivity, and specificity of 0.773, 0.73, and 0.75, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The incidence of SSI after robot\u2010assisted radical cystectomy was significantly lower than that after the open procedure. However, decreased bleeding volume, which was significantly associated with robot\u2010assisted procedures, was an independent and more significant factor for reducing SSI after radical cystectomy than the differences of the surgical procedure even after propensity score matching.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.15382","type":"journal-article","created":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T06:33:27Z","timestamp":1704350007000},"page":"430-437","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Lower bleeding volume contributes to decreasing surgical site infection in radical cystectomy: A propensity score\u2010matched comparison of open versus robot\u2010assisted radical cystectomy"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0069-7392","authenticated-orcid":false,"given":"Jun","family":"Kamei","sequence":"first","affiliation":[{"name":"Department of Urology Jichi Medical University  Tochigi Japan"},{"name":"Department of Urology The University of Tokyo Graduate School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaori","family":"Endo","sequence":"additional","affiliation":[{"name":"Department of Urology Jichi Medical University  Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0433-7105","authenticated-orcid":false,"given":"Masahiro","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Department of Urology Jichi Medical University  Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Sugihara","sequence":"additional","affiliation":[{"name":"Department of Urology Jichi Medical University  Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ei\u2010Ichiro","family":"Takaoka","sequence":"additional","affiliation":[{"name":"Department of Urology 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