{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:37:25Z","timestamp":1777916245397,"version":"3.51.4"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T00:00:00Z","timestamp":1704931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Many congenital hydronephroses spontaneously resolve. This study evaluated a long\u2010term follow\u2010up of more than 4\u2009years of patients with congenital hydronephrosis at a single center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In total, 215 patients (286 kidneys) with congenital hydronephrosis were included. Hydronephrosis outcomes (resolution, improvement, and persistence) and time\u2010to\u2010outcome were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fourteen patient<jats:bold>s<\/jats:bold> underwent early surgical intervention until the age of 2\u2009years. A total of 189 congenital hydronephrosis cases (66%) showed resolution at a median of 16\u2009months (interquartile range: 7\u201321\u2009months) and 169 (80%) of 210 kidneys with grade I to II hydronephrosis showed resolution at a median of 14\u2009months (interquartile range: 6\u201323\u2009months). Of 76 kidneys with grade III to IV hydronephrosis, 24 (32%) showed resolution at a median of 29\u2009months (interquartile range: 24\u201341\u2009months), and 56 (74%) showed improvement to grade II or less at a median of 12\u2009months (interquartile range: 5\u201323\u2009months). Of the 76 kidneys with grade III to IV hydronephrosis, five required delayed pyeloplasty at a median of 66\u2009months (interquartile range: 42\u201389\u2009months). One patient was asymptomatic, with a marked worsening of hydronephrosis and decreased renal function 6\u2009years after the resolution of hydronephrosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>None of the patients with grade I to II hydronephrosis required surgical treatment, and a shorter follow\u2010up may be sufficient. Grade III to IV severe hydronephrosis should be considered for a longer and more careful follow\u2010up, given the possibility of asymptomatic exacerbation of hydronephrosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.15391","type":"journal-article","created":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T12:23:45Z","timestamp":1704975825000},"page":"507-511","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Long\u2010term follow\u2010up of congenital hydronephrosis in a single\u2010center study"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7142-5901","authenticated-orcid":false,"given":"Yosuke","family":"Morizawa","sequence":"first","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Nara Japan"},{"name":"Department of Pediatric Urology Nara Prefecture General Medical Center  Nara Nara Japan"},{"name":"Department of Urology Okanami General 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Urology Nara Medical University  Kashihara Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenta","family":"Onishi","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9514-9964","authenticated-orcid":false,"given":"Shunta","family":"Hori","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6056-3820","authenticated-orcid":false,"given":"Daisuke","family":"Gotoh","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Nara 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