{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:25:53Z","timestamp":1789680353453,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,2,25]],"date-time":"2024-02-25T00:00:00Z","timestamp":1708819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Testicular volume (TV) is known to be one of the main parameters for testicular function (TF). This study was conducted to re\u2010evaluate the indications of a varicocelectomy based on a survey of preoperative TV results in left\u2010side varicocele patients considered to reflect the detrimental effects of a varicocele on TF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>TV results of infertile patients determined using ultrasonography by a single expert physician were retrospectively evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 590 examined patients, 424 had no varicocele findings (Group A), while 148 had a left\u2010side varicocele (Group B). Group B was subdivided based on varicocele grade into Group B0 (subclinical), B1 (grade 1), B2 (grade 2), and B3 (grade 3). Comparisons of left\u2010side TV showed no significant differences for grade among Group A, B0, and B1, whereas that for Group B2 and B3 was significantly lower as compared with Group A (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01, 0.02, respectively). The median TV of Group B I (composed of Groups B0 and B1) was 9.8\u2009cm<jats:sup>3<\/jats:sup>, while that of Group B II (Groups B2 and B3) was significantly lower at 8.4\u2009cm<jats:sup>3<\/jats:sup> (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). In contrast, a comparison of right TV values identified no significant differences among the groups (<jats:italic>p<\/jats:italic>\u2009=\u20090.918).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A varicocelectomy should be performed for patients with a grade 2 and 3 varicocele for ameliorating testicular function.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.15436","type":"journal-article","created":{"date-parts":[[2024,2,25]],"date-time":"2024-02-25T09:29:53Z","timestamp":1708853393000},"page":"670-677","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Significant reduction in left testicular volume shown by ultrasonography in infertile patients with left\u2010side grade 2\u20133 varicocele as compared to less than grade 2: An evidence for indication of varicocelectomy"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8344-577X","authenticated-orcid":false,"given":"Nobuyuki","family":"Kondoh","sequence":"first","affiliation":[{"name":"Advanced Fertility Center of Fuchu Nozomi  Osaka Japan"},{"name":"Kawanishi City Medical Center  Kawanishi Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Chikawa","sequence":"additional","affiliation":[{"name":"Advanced Fertility Center of Fuchu Nozomi  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikiko","family":"Okumura","sequence":"additional","affiliation":[{"name":"Advanced Fertility Center of Fuchu Nozomi  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitomi","family":"Hayakawa","sequence":"additional","affiliation":[{"name":"Advanced Fertility Center of Fuchu Nozomi  Osaka 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