{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:42:28Z","timestamp":1792147348478,"version":"4.4.0"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Detrusor underactivity (DU) is a common cause of lower urinary tract symptoms (LUTS). To date, no consensus has been reached on the urodynamic criteria for defining DU. We previously proposed the area under the curve of the Watts factor (WF\u2010AUC) as a new parameter for diagnosing DU. By comparing previously reported five criteria for DU and WF\u2010AUC, we analyzed whether the WF\u2010AUC could assess detrusor contraction in women with LUTS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using urodynamic data of consecutive 77 women with LUTS, first, we classified DU based on previously reported five criteria. Second, we assessed the potential correlation between multiple parameters and WF\u2010AUC. Third, receiver operating characteristic curve analysis was performed to determine the cutoff value of WF\u2010AUC for diagnosing DU based on previously reported five criteria. Fourth, a linear regression analysis was conducted and compared using multiple criteria and female bladder outlet obstruction index (BOOIf).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>WF\u2010AUC was positively correlated with the maximum values of WF, bladder contractility index (BCI), and projected isovolumetric pressure 1 (PIP1) with correlation coefficients of 0.63, 0.57, and 0.34, respectively. AUC for diagnosing DU based on previously reported five criteria ranging from 0.773 to 0.896 with different cutoff values of AUC\u2010WF. The Spearman's correlation test revealed that BOOIf was significantly correlated with BCI, but not <jats:italic>W<\/jats:italic><jats:sub>max<\/jats:sub>, PIP1 and WF\u2010AUC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study demonstrated the non\u2010inferiority of the WF\u2010AUC compared to previously reported criteria for defining DU. Depending on the cutoff value, the WF\u2010AUC could appropriately evaluate women with DU, regardless of the presence of BOO.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.15531","type":"journal-article","created":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T01:15:41Z","timestamp":1720228541000},"page":"1121-1127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Validation of the area under the Watts factor curve during the voiding cycle as a novel parameter for diagnosing detrusor underactivity in females"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2870-9225","authenticated-orcid":false,"given":"Takeya","family":"Kitta","sequence":"first","affiliation":[{"name":"Department of Renal and Urologic Surgery Asahikawa Medical University  Asahikawa 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